The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $498,713 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the RU School of Osteopathic Medicine. The grant will fund research to investigate the potential impact of a low-fat, high-fiber diet in limiting traumatic brain injury (TBI)-induced neurodegenerative and inflammatory changes, compared to a standard Western diet, in a mouse model with chronic cardiovascular disease and TBI. The research aims to evaluate the effects of these diets on blood-brain barrier function, neuroinflammation, and immune response. In addition, the University of Pennsylvania will receive a $XX,XXX sub-award to contribute expert medical expertise and analysis related to brain injury. The goal is to generate preliminary data demonstrating the beneficial effects of the low-fat, high-fiber diet in reducing the long-term detrimental impacts of TBI.
Generated 3/4/25, 6:17 AM