This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, supports research to investigate the relationship between traumatic brain injury (TBI), hematopoietic stem cell dysfunction, chronic neurodegeneration, and Alzheimer's disease (AD). The $102,948 award, active from December 1, 2024 to August 31, 2027, will employ a clinically...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $571,404.00 to the University of Pittsburgh to conduct research aimed at understanding and improving neurological outcomes after traumatic brain injury (TBI). The key research objectives are to: Evaluate the long-term therapeutic potential of an adiponectin receptor agonist in...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, will fund research at the Augusta University Research Institute, Inc. (doing business as Georgia Health Sciences) to investigate the mechanisms linking traumatic brain injury (TBI) to subsequent neurodegeneration and dementia. The $1,975,262 award will support a 3-year study...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $587,521 in funding to the Regents of the University of Michigan to conduct research on mitochondrial modulation therapy for the treatment of traumatic brain injury (TBI). The key objectives of this 5-year, $587,521 grant are to: (1) explore the molecular mechanisms of...
This Project Grant award, valued at $404,100.00, was issued by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award will support research by The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to investigate the mechanisms of chronic blood-brain barrier dysfunction after traumatic brain injury (TBI). The...
This federal Project Grant award, valued at $405,000.00 and granted by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research focused on understanding the effects of traumatic brain injury (TBI) on serotonin (5-HT) neurotransmission. The research aims to identify and characterize TBI-induced alterations in the transcriptional identity of specific...
The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), awarded a $628,133 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to Rutgers, The State University in New Jersey. The grant, titled "METABOLIC MECHANISMS OF RECOVERY IN MILD TBI", aims to study the molecular mechanisms that mediate injury and protection from mild traumatic brain injury (mTBI) using rodent...
This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program provides $274,855 to Mito-Biotherapeutics, Inc. to develop a novel fusion protein construct that can cross the blood-brain barrier and deliver a therapeutic payload to repair mitochondrial DNA damage in neurons following traumatic brain injury (TBI). The project aims to advance the understanding of bioenergetic dysfunction and its role in...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $556,661 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to the University of Alabama at Birmingham (UAB). The grant supports research to investigate the role of thalamic microglia in driving cognitive impairment after cortical injuries, such as those resulting from traumatic brain injury (TBI). The research aims to elucidate how microglial changes in the...
This Project Grant award, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will fund research to improve the understanding of traumatic brain injury (TBI) biomechanics. The $559,820 award will enable the University of South Carolina, in collaboration with the Henry M. Jackson Foundation for the Advancement of Military Medicine, to conduct a multimodal study...