Project Grant R21HD116483
Award Date
8/6/24
Completion Date
7/31/26
Dollars Obligated
$244K
Federal Agency
National Institute of Child Health and Human Development
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Philadelphia, PA 19104, USA
Similar Awards
This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) will support research by a postdoctoral fellow at Rutgers University to investigate the molecular mechanisms underlying fertilization and egg activation. The $133,207 award, effective from August 9, 2024 to July 31, 2026, will fund three specific research aims: 1) determining the function of the PGM-3 protein in the oocyte, 2) exploring...
This Project Grant award, valued at $441,505.00, was awarded on August 16, 2024 by the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award supports research at the University of Pittsburgh to uncover the molecular mechanisms by which zinc regulates mammalian sperm physiology, particularly with respect to sperm swimming and fertilization. The central objectives are to: 1) establish the...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will provide $1,080,375 to the University of Massachusetts Medical School (UMass Medical) to conduct research on the role of maternal transcripts and RNA-binding proteins in reproductive fecundity. The primary objective is to comprehensively explore how fluctuating environmental factors, particularly...
This federal Project Grant award, valued at $418,194.00 and granted by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to uncover the developmental and molecular mechanisms underlying the establishment and maintenance of the ovarian follicle reserve. The research aims to better understand, diagnose, and potentially manage conditions like primary ovarian insufficiency and...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $760,617 in funding to Boston Children's Hospital to conduct research on the mechanisms underlying pluripotency transitions during peri-implantation embryonic development. The research aims to identify key transcription factors and elucidate the epigenetic regulation involved in the transitions...
This Project Grant award from the National Institute of Child Health and Human Development, under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to investigate the role of microRNAs in follicular extracellular vesicles and their potential therapeutic applications for oocyte cryopreservation. The award, totaling $255,458, will fund a series of studies at the Smithsonian Institution to elucidate the physiological significance of follicular fluid...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 - Child Health and Human Development Extramural Research program provides $658,633 to Wayne State University to conduct research on the mechanisms of the MEIG1 protein complex in mammalian spermiogenesis and fertilization. The key objectives are to: Dissect the motor-based protein complex in the manchette (a spermatid-specific structure) and study its role in sperm formation;...
This $335,955 federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to understand the mechanisms by which calcium triggers the transition from a mature egg cell to an activated embryo capable of development. The award to Cornell University, which began on December 9, 2024 and runs through November 30, 2029, will fund investigations into the role...
This federal Project Grant award, with ID F31HD113347, is funded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research (CFDA 93.865) program. The award, totaling $160,877, supports research on the role of histone demethylase enzymes in the development of primordial germ cells during mouse embryonic development. The research aims to elucidate the mechanisms of epigenetic remodeling, including the removal of...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $1,713,959.00 to Albert Einstein College of Medicine to conduct research on sperm chromatin structure and remodeling during spermiogenesis and fertilization. The research aims to provide a comprehensive biochemical and biological characterization of the factors that mediate the assembly and...