This Project Grant award of $2,163,115 from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) will support research to characterize the epigenomic landscapes and genetic mechanisms underlying different stages of endometriosis. The principal recipient, the University of Texas Health Science Center at San Antonio, will perform large-scale single-cell epigenomic profiling, allele-specific gene regulation analysis, and...
The National Institute of Child Health and Human Development (NICHD) awarded a $2,344,039 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to the Fred Hutchinson Cancer Center in Seattle, WA. The grant is titled "Examination of Factors Influencing the Racial Disparity in Fibroid Incidence" and will study uterine fibroids, which are 2-3 times more common in Black women compared to White women. Over 5 years, the project will analyze data from two large...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to identify the central and peripheral mechanisms underlying endometriosis pain and changes in pain after lesion removal surgery. The $233,250 award to The Washington University in St. Louis will fund a study to examine the relationship between local and systemic estrogen levels, estrogen...
The National Institute of Child Health and Human Development (NICHD) awarded a $2,045,782 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Endomet Biosciences, Inc., a woman-owned small business located in Irvine, California. The grant supports the development of a novel, non-hormonal therapeutic called ENDO-205 for the treatment of endometriosis, a prevalent and debilitating women's health condition that currently lacks an effective cure....
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $643,049 to the University of Illinois to develop a physiomimetic model of the endometrioma lesion microenvironment. The objective is to investigate the processes responsible for the initiation and invasion of endometriosis lesions, which are a common yet poorly understood gynecological condition...
This Project Grant award of $268,065 from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) will support research to investigate the association between childhood sexual abuse (CSA) and the risk of developing uterine leiomyomata (UL), endometriosis, and polycystic ovarian syndrome (PCOS) in a North American cohort. The study will leverage the existing Pregnancy Study Online (PRESTO) infrastructure, which has...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to examine the association between adverse childhood experiences (ACEs) and the development and growth of uterine fibroids among Black/African American women. The $229,393 award to the University of North Carolina at Chapel Hill will be used to: 1) describe the prevalence of ACEs and...
This Project Grant award from the National Human Genome Research Institute (NHGRI), under the Human Genome Research (CFDA 93.172) program, provides $794,894 to fund research on hormonal influences on inflammation in endometriosis. The key products and services to be delivered include: Utilizing existing research infrastructure to collect endometriosis tissue samples, eutopic endometrium, peritoneal fluid, and peripheral blood for genetic analysis and multi-omic profiling. This will involve...
This $1,386,091 federal Project Grant award from the Department of Defense's Military Medical Research and Development program (CFDA 12.420) is funding a research project at the University of Miami to study awareness and knowledge of endometrial cancer among subpopulations of Black women. The project will be conducted over a performance period from July 1, 2024 to June 30, 2027. As a prominent academic medical center, the University of Miami has extensive experience executing federally-funded...
The National Institute of Child Health and Human Development (NICHD) awarded a $759,944 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Nextgenjane Inc., a women's health startup, to develop a non-invasive diagnostic test for endometriosis. The funding will support validation studies of Nextgenjane's high-performance genomic assay for endometriosis detection using menstrual effluence samples from infertility patients. As a subawardee, Nextgenjane...