Project Grant R21HD113527
- The National Institute of Child Health and Human Development (NICHD) awarded a $411,125 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Syracuse University to develop a microfluidic human placenta organoid model. The goal is to generate human trophoblast stem cells (HTSCs) from induced pluripotent stem cells and use them to create a placenta organoid system that can replicate early/mid-gestation placental development. The researchers will study the role of...
- The U.S. National Institute of Child Health and Human Development (NICHD) awarded a $766,982 Project Grant to Carnegie Mellon University under the Child Health and Human Development Extramural Research program (CFDA 93.865). The project aims to develop and validate a novel computational framework to simulate uteroplacental hemodynamics and placentation, with the goal of identifying metrics for early detection of pregnancy complications related to abnormal placental formation. This research...
- This $429,000 federal Project Grant award, funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the gene and environmental influences on placental angiogenesis and severe fetal growth restriction. The University of Colorado-Denver, the awardee organization, will leverage induced pluripotent stem cell technology to better...
- This $163,145 Project Grant awarded on August 7, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research Program (CFDA 93.865), aims to address critical questions pertaining to impaired placentation associated with fetal growth restriction (FGR). The principal investigator, a pediatric and fetal surgeon, will use this 5-year award to develop unique cross-disciplinary skills and...
- The National Institute of Child Health and Human Development (NICHD) awarded a $429,000 Project Grant (CFDA 93.865: Child Health and Human Development Extramural Research) to Thomas Jefferson University, doing business as Sidney Kimmel Medical College, to develop a new imaging tool to assess placental hemodynamics during pregnancy. The study aims to determine if Subharmonic Aided Pressure Estimation (SHAPE) using contrast-enhanced ultrasound can provide a safe, non-invasive, and real-time method...
- The federal Project Grant award of $429,000 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to characterize placental extracellular vesicles (EVs) throughout human pregnancy. The goal is to develop novel methods to image, count, isolate, and validate placental cell- and size-specific EVs from maternal blood, in order to monitor placental...
- The University of California, San Diego (UCSD) received a $151,040 Project Grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant, awarded on January 25, 2026, with a completion date of July 31, 2027, supports research to investigate the effects of rare damaging mutations in TGFβ latent complex proteins found in preeclamptic placentas. The key...
- The U.S. National Institute of Child Health and Human Development (NICHD) awarded a $735,531 Project Grant titled "FAMILY INPUT FOR QUALITY AND SAFETY DISSEMINATION AND IMPLEMENTATION" to the Regents of the University of California, San Francisco (UCSF). The project aims to address outstanding dissemination and implementation questions for a mobile phone-based approach called the Family Input for Quality and Safety (FIQS) that engages families and patients to report on safety issues in...
- This $1,367,400 Cooperative Agreement, awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports the UC San Diego Center for Stillbirth Prevention in conducting research on maternal and placental determinants of fetal growth restriction (FGR). The goal is to develop a maternal serum-based test for antepartum identification of placental dysfunction and FGR, which are...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $2,255,352 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Regents of the University of Colorado, doing business as the University of Colorado-Denver. The award, effective September 15, 2025 through May 31, 2028, will fund research to determine the cellular and molecular mechanisms involved in the transfer of inflammatory signals across...
The National Institute of Child Health and Human Development (NICHD) awarded a $461,780 R21 project grant (CFDA 93.865: Child Health and Human Development Extramural Research) to The Regents of the University of California, San Francisco (UCSF) on August 1, 2023 to investigate the feasibility of a clinical-scale, anticoagulation-free artificial placenta device. The project aims to overcome key barriers to the clinical translation of artificial placenta technology, which is designed to simulate intrauterine physiology and enable continued normal development for extremely preterm infants outside the uterus. The research will utilize a novel microfluidic artificial placenta oxygenator based on semiconductor silicon-based semi-permeable membranes, with the goal of operating without requiring high-risk anticoagulation. The project involves a combination of computational modeling, benchtop studies, and preclinical in-vivo evaluations. UCSF will also collaborate with The Nemours Foundation under a $177,777 sub-grant to design and evaluate a hemocompatible blood flow path for the artificial placenta device.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $461.8k | 8/1/23 |
GrantNumber | Description | Subgrantee | Prime Award | Dollars Obligated | Updated At |
|---|---|---|---|---|---|
14777SCS | The Nemours Foundation | Project Grant R21HD113527 | $135.4k | 11/13/23 |