Project Grant R01HD120113
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), is funding research to investigate how the maternal immune response to influenza virus infection during pregnancy can impact fetal brain development. The overarching goal is to identify potential therapeutic targets within the transplacental immune signaling pathways that could be...
- This $163,145 Project Grant awarded on August 7, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research Program (CFDA 93.865), aims to address critical questions pertaining to impaired placentation associated with fetal growth restriction (FGR). The principal investigator, a pediatric and fetal surgeon, will use this 5-year award to develop unique cross-disciplinary skills and...
- This Project Grant award of $226,608.00 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) is funding research to identify the mechanistic link between fetal glucagon and placental nutrient delivery. The goal is to establish how fetal glucagon regulates placental lactogen secretion and uterine blood flow as an adaptive mechanism for matching nutrient supply to...
- This $429,000 federal Project Grant award, funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the gene and environmental influences on placental angiogenesis and severe fetal growth restriction. The University of Colorado-Denver, the awardee organization, will leverage induced pluripotent stem cell technology to better...
- This federal Project Grant award, funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), is supporting research on the role of decidual extracellular vesicles in mediating placental insufficiency. The $654,671 award, which commenced on August 1, 2025 and is scheduled for completion by April 30, 2030, is being conducted by the awardee, Yale University. The key...
- This $293,550 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), is funding research to investigate the effect of inherited maternal cells on BCG-specific T cell responses in HIV-exposed and unexposed infants. The award supports a study hypothesizing that reduced transmission of maternal microchimerism in utero may be a mechanism...
- The Trustees of Columbia University in the City of New York received a $452,375 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research Federal Grant Program (CFDA 93.865). The award, effective from August 1, 2025 to July 31, 2027, supports research to investigate the reciprocal interactions between placental neurosteroid allopregnanolone and placental inflammatory...
- The National Institute of Child Health and Human Development (NICHD) has awarded a $423,985 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Illinois to develop a novel non-invasive monitoring system for detecting placental dysfunction and associated pregnancy complications. The funding will support research to utilize extracellular vesicles (EVs) circulating in maternal blood as biomarkers, using a "target recycling...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $232,500 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Johns Hopkins University. The grant supports research to investigate the virologic determinants that lead to long-term antiretroviral therapy-free control in a subset of infants infected with HIV-1 in utero. Key research activities include: Creating infectious molecular clones...
- The University of Colorado received a $127,266 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The 2.5-year grant, awarded on September 27, 2025, supports research to investigate the role of insulin receptor substrate 1 (IRS-1) in regulating embryonic glucose homeostasis and its relationship to neural tube defect (NTD) risk. The study aims...
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $2,255,352 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Regents of the University of Colorado, doing business as the University of Colorado-Denver. The award, effective September 15, 2025 through May 31, 2028, will fund research to determine the cellular and molecular mechanisms involved in the transfer of inflammatory signals across the maternal-fetal interface during viral infections. The research aims to profile transcriptomic signatures of maternal and fetal cell types in placentas, compare inflammatory biomarkers in maternal and infant samples, and characterize the impact of inflammatory signaling on placental function and fetal development. The findings could help elucidate how maternal inflammatory disorders, including infections, can adversely impact infant health outcomes in the absence of direct fetal infection.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.3m | 9/20/25 | ||
| Not listed | ($791k) | 9/17/25 | ||
| Not listed | $791.1k | 9/15/25 |