Project Grant R21EY037948
- The National Eye Institute (NEI) has awarded a $423,500 Project Grant to The Leland Stanford Junior University (Stanford University) to validate the use of Transcranial Ultrasound Stimulation (TUS) for noninvasive neuromodulation of the subcortical visual pathways in humans. The project, titled "Noninvasive Neuromodulation of Subcortical Visual Pathways with Transcranial Focused Ultrasound", will be conducted from September 1, 2025 to August 31, 2027 under the NEI's Vision Research...
- This $423,500 federal Project Grant award from the National Eye Institute's (NEI) Vision Research program supports research at Stanford University to precisely measure the physiological impact of transcranial ultrasound stimulation (TUS) on the human brain. The research aims to quantify the hemodynamic, neurometabolic, and thermal effects of TUS on the visual system, using advanced neuroimaging techniques such as MR-acoustic radiation force imaging (ARFI), BOLD, arterial spin labeling (ASL), and...
- The National Eye Institute (NEI), under the Department of Health and Human Services, has awarded a $695,050 Project Grant to The Leland Stanford Junior University (Stanford University) to investigate the role of cholinergic dysfunction in the pathogenesis of glaucoma. The grant, funded through the NEI's Vision Research program (CFDA 93.867), aims to leverage advanced magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques to identify and quantify cholinergic changes in the visual...
- The National Eye Institute (NEI) awarded a Project Grant of $864,040 to The Leland Stanford Junior University (Stanford University) on July 1, 2025 under the NEI's Vision Research program (CFDA 93.867). The project aims to develop and test an intraocular projection system that can be implanted in the eye to restore vision in patients with severe corneal injury or damage. The key objectives of the 5-year project are: Build and implant 25 dummy lenticule implants of varying weights in rabbits to...
- The U.S. National Eye Institute (NEI) awarded a Project Grant under the Vision Research federal grant program (CFDA 93.867) to The Leland Stanford Junior University (Stanford University) in the amount of $257,785. The grant supports research to investigate the role of DNA damage response pathways, specifically the inhibition of checkpoint kinase 1 (CHK1), in enhancing retinal ganglion cell survival and promoting neuroprotection for the treatment of traumatic optic neuropathy (TON). The...
- The National Eye Institute (NEI) awarded a $421,136 Project Grant to the University of Maryland, College Park under the Vision Research federal grant program (CFDA 93.867) to explore a novel approach for correcting ocular opacities and enabling high-resolution fundus imaging. The 2-year project aims to demonstrate that neural-network based wavefront shaping can optically correct for ocular opacities, which degrade the performance of optical imaging techniques for the posterior segment of the...
- The National Eye Institute (NEI), part of the Department of Health and Human Services, awarded a $113,274 Project Grant to the Texas A&M University System Health Science Center (TAMU HSC) under the Vision Research federal grant program (CFDA 93.867). The grant, awarded on June 1, 2025, aims to develop innovative surgical techniques using ultrafast, nonthermal lasers for treating vitreoretinal and posterior segment disorders of the eye. The project will evaluate the use of femtosecond...
- The National Eye Institute (NEI) awarded a $602,198 Project Grant under its Vision Research program (CFDA 93.867) to the University of Southern California (USC) to develop an "Attentive Knowledge Device for Visual Assistance" - an artificial intelligence (AI)-powered smartphone app and smart eyeglasses system to better assist people with visual impairments. The project aims to leverage machine vision algorithms and AI techniques to proactively integrate real-time visual information...
- The National Eye Institute (NEI) awarded a $451,000 Project Grant under the Vision Research federal grant program (CFDA 93.867) to The Regents of the University of California, San Francisco (UCSF) to conduct a multimodal characterization of a novel inherited mouse model of glaucoma. The research aims to evaluate structural and functional changes in the mouse model, including axonal degeneration, retinal ganglion cell loss, dendritic changes, and neuroinflammatory responses. It will also identify...
- The National Eye Institute (NEI), under the U.S. Department of Health and Human Services, awarded a $606,092 Project Grant through the Vision Research program (CFDA 93.867) to The Regents of the University of California, doing business as the University of California, Berkeley (UC Berkeley). The grant, awarded on January 1, 2025, supports a 4-year research project to investigate the development of the preferred retinal locus (PRL) in individuals with central vision loss due to macular diseases...
The National Eye Institute (NEI), a part of the U.S. Department of Health and Human Services, awarded a $617,743 Project Grant under the Vision Research program (CFDA 93.867) to The Leland Stanford Junior University to study the effects of ultrasound stimulation on retinal ganglion cell activity. The goal is to use a newly developed transparent ultrasound transducer, together with in vivo optical imaging, to understand the biophysical mechanisms and therapeutic potential of ultrasound for neuroprotection and vision preservation. The project aims to determine effective ultrasound parameters, test its physical mechanisms, and explore clinical applications in animal models. This multidisciplinary research leverages Stanford's expertise in transducer fabrication, ultrasound neuromodulation, retinal physiology, and optic nerve disease to address a critical need for understanding how ultrasound affects neural activity in the eye.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $617.7k | 8/14/25 |