This federal Project Grant award from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) provides $1,765,704.00 to develop an injectable optoacoustic retina prosthesis for high-precision retinal stimulation. The primary awardee, Trustees of Boston University, will collaborate with Fondation Voir Et Entendre as a sub-awardee to test the safety and efficacy of the injectable prosthesis in rodent models. The key objectives are to create a biocompatible, minimally...
This Project Grant award from the National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), provides $306,118 to Eyescreen, Inc. to develop a new drug screening platform using viable human donor eyes. The key goals are to: Establish ex vivo preclinical models for human ocular diseases by restoring and preserving in vivo-like light responsiveness in postmortem human eyes procured up to 1 hour and stored for over 48 hours. Develop a high-throughput screening...
This Project Grant award from the National Eye Institute (NEI), under the Federal Grant Program for Vision Research (CFDA 93.867), will support research to develop therapies that regenerate lost connections between the eye and brain to restore vision. The total funding of $499,116 will be provided to the University of California, San Diego (UCSD) from September 1, 2024 to August 31, 2029. The key objectives are to: 1) Determine the ability of neural stem cell-derived neuronal relays transplanted...
This $232,500 Project Grant awarded by the National Eye Institute (NEI) under the Vision Research federal grant program (CFDA 93.867) supports research to investigate the ability to restore 3D object perception through patterned micro-stimulation of intermediate and higher-level visual cortex. The grantee, The Johns Hopkins University, will conduct experiments in macaque monkeys to test the hypothesis that micro-stimulation of specific V4 neural clusters encoding 3D geometric object fragments...
This Project Grant award from the National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), provides $237,996 to The Regents of the University of Colorado (CU) to develop innovative high-resolution, wide-field corneal imaging capabilities. The key objective is to investigate speckle illumination holographic imaging techniques that can capture 3D information on corneal structures, including polarization-sensitive data, to enable better visualization and assessment of cellular...
This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) provides USD 1,707,487 to the University of Michigan to advance intraretinal electrical stimulation techniques for high-acuity artificial vision. The research aims to overcome limitations of current retinal prostheses by developing an innovative high-density carbon fiber electrode array that can be precisely positioned within the inner retinal layers. The goal is to achieve 20/160 visual acuity, a...
This Project Grant award from the National Eye Institute (CFDA 93.867 Vision Research) provides $881,796 to Siloam Vision, Inc. to develop two advanced, laser-based, AI-enabled retinal imaging systems. The key innovations include: A wider field-of-view camera design that can be paired with either a scanning laser ophthalmoscope (SLO) or optical coherence tomography (OCT) system, offering 2D or 3D imaging of the entire retina without requiring pupil dilation. Super-resolution AI algorithms to...
This Project Grant award from the National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), supports a collaboration between the University of Northern Colorado (UNC) and researchers to develop novel biophysical models of eye morphogenesis processes. The $413,920 award, effective August 1, 2024 through July 31, 2027, will fund the creation and validation of quantitative models for choroid fissure closure in zebrafish and foveal pit formation across species. Key...
This federal Project Grant award from the National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), provides approximately $606,025 to William Marsh Rice University to conduct research on developing a high-resolution visual prosthesis that can restore vision for blind individuals. The key objectives of this 5-year project are to: Examine the perceptual properties and visual field coverage of phosphenes (perceived flashes of light) elicited by microstimulation of the...
The National Eye Institute (NEI) awarded a $441,250 Project Grant under the Vision Research federal grant program (CFDA 93.867) to the University of Washington to support a research project titled "Photoreceptor Induction in Wounded Corneas". The research aims to investigate how light modulates corneal wound healing through an opsin-dependent mechanism, with the goal of developing therapeutic approaches to facilitate wound closure and prevent scarring. The project will utilize in...