Project Grant R21EY037547
- The National Eye Institute (NEI), under the federal Vision Research grant program (CFDA 93.867), awarded a $431,750 Project Grant to the University of Louisville to study the role of neurexin proteins in retinal structure and function. The grant, effective from September 1, 2025 to August 31, 2027, aims to 1) determine the function of three neurexin genes and their isoform-specific expression patterns within the retina, and 2) characterize the cell-type-specific expression of neurexin isoforms...
- This $427,625 Project Grant awarded by the National Eye Institute's Vision Research program on September 1, 2025 will support research to investigate the interplay between debris/dying cell clearance by specific retinal phagocytes and the potential for improving tissue healing in oxygen-induced retinopathy (OIR). The research, to be conducted by The Washington University, aims to determine whether cell-type specific expression of a chimeric efferocytosis (CHEF) receptor in Müller cells versus...
- This Project Grant award from the National Eye Institute (NEI), part of the U.S. Department of Health and Human Services, provides $385,000.00 in funding to Wayne State University to conduct research on genetic and glial support mechanisms in acute and chronic models of photoreceptor degeneration. The research aims to understand, prevent, and treat vision-related conditions and diseases, a focus area of NEI's Vision Research federal grant program (CFDA 93.867). The study will compare...
- This Project Grant award for $679,159 from the National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), supports research on in vivo epigenetic reprogramming of retinal ganglion cells (RGCs) in aging mice with glaucoma. The research aims to identify new therapeutic targets for glaucoma that can protect and rejuvenate RGCs, which are specifically targeted and damaged in this disease leading to vision loss. The 4-year project, awarded to The Schepens Eye...
- The National Eye Institute (NEI), under the federal Vision Research grant program (CFDA 93.867), awarded a $595,302 project grant to Thomas Jefferson University, doing business as Sidney Kimmel Medical College, for the period of April 1, 2025 to March 31, 2030. The project aims to investigate how glucose and lactate support photoreceptor health and function in order to develop new treatment strategies to prevent vision loss. Specifically, the researchers will determine whether the retinal...
- This Project Grant award of $568,122.00, provided by the National Eye Institute (CFDA 93.867 - Vision Research), supports research at Baylor College of Medicine to unequivocally confirm the contribution of the neurovascular unit to glaucoma pathogenesis and identify endothelial cell-specific ligands with potential for neuroprotective therapy. The research aims to globally map ligands binding to ocular hypertension and healthy retinal cells, systematically identifying ocular...
- The National Eye Institute (NEI) awarded a $437,310 Project Grant under the Vision Research federal grant program (CFDA 93.867) to the University of Rochester to conduct research on the molecular and physiological mechanisms of inner retinal remodeling in retinal degeneration. The research aims to elucidate the mechanisms behind genetic, morphological, and physiological changes in retinal ganglion cells that lead to decreased signal-to-noise ratio and corruption of retinal circuits, with the...
- This Project Grant award from the National Eye Institute's Vision Research program (CFDA 93.867) is supporting research at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University to investigate the role of neuronal activity on retinal angiogenesis and blood-retina barrier (BRB) maturation. The $248,999 award, effective from May 1, 2025 to April 30, 2028, aims to elucidate how neuronal synaptic activity, specifically cholinergic and glutamatergic neurotransmitters,...
- This $1,369,974 Project Grant was awarded on September 15, 2025 by the National Eye Institute (NEI) under the Vision Research federal grant program (CFDA 93.867) to the West Virginia University Research Corporation (WVURC). The funding supports a 3-year research project to investigate therapies for defects in protein networks essential for the development of photoreceptor outer segments, a key component of photoreceptor neurons responsible for vision. The research aims to identify an optimal...
- The National Eye Institute (NEI) awarded a $451,000 Project Grant under the Vision Research federal grant program (CFDA 93.867) to the University of Chicago. The grant supports the "Development of the RGC Projectome" project, which aims to create comprehensive models describing how hundreds of thousands of retinal ganglion cell (RGC) axons faithfully grow in the proper direction during embryogenesis to establish proper vision. This research is critical, as disruptions in this process...
This $422,125 Project Grant award from the National Eye Institute's Vision Research program is funding research to investigate the role of cholesterol homeostasis in the treatment of demyelinating eye diseases. The research aims to develop neuroprotective and neuroreparative therapies that can prevent retinal ganglion cell degeneration and promote remyelination to preserve visual function. The award was made to the University of Miami, which has extensive expertise in providing specialized medical services and conducting federally-funded biomedical research. This project represents a 2-year effort from August 2025 to July 2027 to advance the understanding of the underlying pathological processes and repair mechanisms in demyelinating eye diseases.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $422.1k | 7/29/25 |