Project Grant R21EY037337
- Federal Grant Award Summary The National Eye Institute (NEI) awarded $984,000 to The Regents of the University of California, San Francisco under the Vision Research program (CFDA 93.867) on September 30, 2025, for a planning and feasibility study on decentralized dry eye disease (DED) clinical trials. This R34 award, extending through September 29, 2027, will produce three primary deliverables: (1) development of a remote trial design framework enabling decentralized recruitment and study of...
- Federal Grant Award Summary Augusta University Research Institute, Inc. received a $495,229 Project Grant from the National Eye Institute under the Vision Research program (CFDA 93.867) beginning April 1, 2026 and concluding February 28, 2029. The primary deliverables include the development of molecular-based diagnostic subtypes for dry eye disease (DED) through advanced proteomic analysis and machine learning classification. The project will employ high-resolution liquid...
- Federal Project Grant Award Summary The National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) awarded $902,000 to the University of California, San Francisco for a two-year project (September 1, 2025 – August 31, 2027) to conduct multimodal characterization of a novel inherited mouse model of glaucoma. The primary deliverables include comprehensive phenotypic characterization of GLIS1 knockout mice across two genetic backgrounds, evaluating structural and functional...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded a Project Grant totaling $900,600 to The Regents of the University of California, San Francisco, with an award date of September 1, 2025, and completion date of August 31, 2027, under the Vision Research program (CFDA 93.867). This award funds research directed at understanding corneal limbal stem cells (LSCs) during wound healing processes. The project addresses the significant clinical need for restorative treatments for...
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded $255,722 under the Vision Research program (CFDA 93.867) to the University of California, Berkeley, effective September 15, 2025, through August 31, 2027. This Project Grant supports fundamental research investigating the role and regulation of optic nerve microglia in glaucomatous neuropathy. The research deliverables include scientific findings on how lipoxin B4 (LXB4), an endogenous lipoxin produced by retinal...
- Federal Grant Award Summary The National Eye Institute (Vision Research program, CFDA 93.867) awarded Icahn School of Medicine at Mount Sinai a $1,488,864 Project Grant effective September 1, 2025 through June 30, 2028 to conduct research on the epigenetic regulation of the meibomian gland in homeostasis and aging. The research aims to delineate epigenetic mechanisms controlling meibomian gland homeostasis and dysregulated in aging, with the ultimate goal of developing therapeutic...
- Federal Project Grant Award Summary The National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) awarded $733,137 to the University of California, Los Angeles on September 15, 2025, to support research exploring how genetic variation influences disease progression and therapeutic response in age-related macular degeneration (AMD). The project, with completion targeted for March 31, 2030, will deliver scientific research products including refined classification of AMD...
- Federal Grant Award Summary The University of California, San Francisco received a $130,182 Project Grant from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) for the period April 1, 2026 through March 31, 2028. This research project focuses on identifying and characterizing neurons in the adult and developing primary visual cortex (V1) that receive bottom-up sensory inputs from the thalamus or top-down predictive inputs from higher visual areas. The research...
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded the University of California, Davis $423,767 under the Vision Research program (CFDA 93.867) for a two-year project period beginning June 1, 2025 and concluding May 31, 2027. The research project investigates the role of myeloid cells as mediators of glaucomatous axon degeneration and evaluates whether nicotinamide adenine dinucleotide (NAD+)-boosting interventions provide neuroprotection through anti-inflammatory...
- Federal Grant Award Summary Award Details: The National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), awarded Michigan State University $869,589 for a three-year project period (May 1, 2025 – April 30, 2028) to develop and validate a new animal model for studying evaporative dry eye disease (EDED). Research Products and Services: This project will establish EDED pathogenesis research capabilities through characterization of AWAT2 knockout (KO) mice, which...
The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $451,000 to The Regents of the University of California, San Francisco on April 1, 2026, for a two-year research project concluding March 31, 2028. This project delivers advanced diagnostic research services through phage immunoprecipitation sequencing (PHIP-SEQ) analysis to identify autoantibodies associated with Sjögren's disease, particularly as it manifests as dry eye disease (DED). The research utilizes tear samples collected from over 700 participants in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort at baseline and at two-year follow-up intervals to profile antibody repertoires and pinpoint autoantigen targets with high-resolution precision. The primary deliverables include comprehensive proteomic analysis results that distinguish Sjögren's disease from other causes of dry eye disease, with a specific focus on female patient populations. By employing high-throughput sequencing integrated with oligonucleotide library synthesis in bacteriophages, the research aims to advance diagnostic capabilities and identify persistent autoantibody markers, thereby supporting improved early detection and therapeutic strategies for this condition.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $451.0k | 4/2/26 |