The National Eye Institute (NEI) awarded a $433,125 federal Project Grant (CFDA 93.867 - Vision Research) to The Ohio State University to leverage data from the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) study to address critical clinical questions in myopia control. The funded research aims to analyze axial length data to determine whom to treat and whether myopia control treatments are beneficial, assess the effects of time spent outdoors and sports...
This $148,568 Project Grant awarded on February 1, 2025 by the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) will support research by Emory University to investigate the role of scleral fibroblasts in refractive development and myopia. The project aims to: 1) identify characteristics of scleral fibroblasts in emmetropic (normal) eyes versus those exposed to myopic stimuli, and 2) determine the role of retinoic acid signaling in driving myopia development. The...
The National Eye Institute (NEI) awarded a $494,418 Project Grant (CFDA 93.867 - Vision Research) to the University of Alabama at Birmingham (UAB) effective February 1, 2025 through January 31, 2029. The project aims to: 1) Determine the anti-myopia effectiveness of a range of real-world visual scenes; 2) Develop an improved repeated low-level red light (RLRL) anti-myopia therapy; and 3) Develop objective recommendations for lighting spectra that could impact refractive development. Using tree...
This Project Grant award, titled "Pilot Test of a Novel Wavelength-Based Method to Control Childhood Myopia," is funded by the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867). The $816,750 grant, awarded on September 30, 2024, supports a pilot study to evaluate the efficacy of amber light exposure in slowing myopia progression and axial elongation in 40 myopic children aged 8 to 12 years. The goal is to test the hypothesis that longer wavelength light,...
The National Eye Institute (NEI) has awarded a four-year, $543,037 Project Grant under the Vision Research program (CFDA 93.867) to New York University School of Medicine to support research aimed at developing a better understanding of the development and function of corneal lens-secreting cells. This research will leverage the power of genetic model organisms, such as Drosophila, to investigate the underlying mechanisms that regulate corneal cell differentiation and the organization of corneal...
This $198,608 federal Project Grant award from the National Eye Institute (NEI) Vision Research program (CFDA 93.867) supports research at the University of Maryland, College Park to combine optical coherence elastography (OCE) and Brillouin microscopy techniques to evaluate in vivo lens biomechanics related to presbyopia. The key objectives are to: 1) develop a combined OCE/Brillouin system capable of quantitatively measuring the depth-dependent elastic moduli of the human lens, 2) validate the...
The National Eye Institute (NEI) awarded a $256,296 Project Grant (CFDA 93.867 - Vision Research) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to develop and validate new "AUTO-SENSING, INSTANTANEOUS ADAPTIVE RANGING OCT" technology. This two-year project aims to expand the imaging depth range of optical coherence tomography angiography (OCTA) systems, enabling improved visualization of the critical peripheral retinal microvasculature...
The National Eye Institute (NEI) awarded a $713,964 Project Grant under the Vision Research program (CFDA 93.867) to The Regents of the University of California, San Francisco (UCSF). The objective of this 5-year award, effective March 1, 2025, is to develop a prototype of a contact lens-based intraocular pressure (IOP) sensor using atomic force microscopy. The project aims to create an accurate, safe, and wearable IOP monitor that can measure IOP with 0.1-1 mmHg precision, improving the...
The National Eye Institute (NEI) awarded a Project Grant (CFDA 93.867 Vision Research) totaling $425,000.00 to the Massachusetts Eye and Ear Infirmary to develop a rapid, culture-independent diagnostic approach for detecting pathogens and antimicrobial resistance in sight-threatening ocular infections. The project aims to create a point-of-care metagenomic sequencing platform using the portable Nanopore sequencer to enable timely and accurate diagnosis of ocular infections, reducing the need for...
The National Eye Institute (NEI) awarded a $245,243 Project Grant (CFDA 93.867 - Vision Research) to Duke University to develop and validate a novel method for measuring ocular pulse amplitude (OPA) using fixed force applanation tonometry. The project aims to: 1) validate the applanation-based OPA measurement technique on non-human primates implanted with an intraocular pressure telemetry system in normotensive and hypertensive eyes, and 2) assess the repeatability and reproducibility of the OPA...