This Project Grant award from the National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), aims to develop a rapid, culture-independent diagnostic approach for detecting pathogens and antimicrobial resistance in sight-threatening ocular infections. The $425,000 award, effective August 1, 2024 through July 31, 2029, will support the Massachusetts Eye and Ear Infirmary in creating a metagenomic sequencing-based platform that uses portable nanopore sequencers to provide comprehensive and timely detection of bacteria, fungi, and Acanthamoeba from ocular samples. This innovative diagnostic tool has the potential to transform ocular infection management from an empirical approach to a more precise, patient-tailored treatment, helping to address the growing challenge of antimicrobial resistance and improve clinical outcomes for patients with sight-threatening infections.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $425.0k | 7/29/24 |