This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173), will support research to define the spatial distribution and molecular characteristics of SOX10+ taste bud progenitor cells in the von Ebner's glands, as well as investigate the regulatory role of the SOX10 transcription factor in the differentiation of these progenitors into taste bud cells. The $377,681 award, with a project period from June 1, 2025 to March 31, 2027, will leverage advanced techniques such as inducible transgenic mouse lines, spatial transcriptomics, and CRISPR/Cas9 technology to achieve these research goals. The findings will enhance understanding of the maintenance of taste bud homeostasis and contribute to the field of communication disorders research.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $377.7k | 5/16/25 |