Project Grant R21DC022725

Award Date 6/1/25
Completion Date 3/31/27
Dollars Obligated $378K
Federal Grant Program
93.173
Assistance Type
Project Grant
Place of Performance
Georgia, USA
Similar Awards
This Project Grant award was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the federal Research Related to Deafness and Communication Disorders Program (CFDA 93.173). The $111,697 award will fund research to identify the role of SOX9 as a marker of multipotent progenitor cells in the homeostasis of the circumvallate papilla (CVP) and von Ebner's minor salivary glands (VEG) in the tongue. The research aims to use genetic barcoding, single-cell...
This $429,000 Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports the establishment of human taste organoid models. The primary objectives are to: Validate and characterize circumvallate papillae (CVP) samples from postmortem human donor tissue to profile taste receptor cells and stem cell populations. This will involve transcriptional profiling...
This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $379,862 to the University of Georgia Research Foundation, Inc. to investigate the role of connective tissue signals in regulating the cell renewal of mature taste buds in adult animals. The project aims to use in vivo and ex vivo systems to examine the effects of cell products from neural...
This federal Project Grant award of $682,219 from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports research aimed at defining mechanisms driving olfactory neuronal homeostasis and dysfunction in humans. The research will identify organized patterns of gene expression in olfactory neurons isolated from human biopsies, both in healthy controls and individuals with...
This federal Project Grant award of $702,560.00 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The award will fund a research project at Brandeis University focused on probing the molecular and genetic mechanisms of invertebrate sugar detection, with a specific focus on gustatory receptors (GRs) in Drosophila. The key objectives are to: 1) investigate the...
This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), will support research into the mechanisms of odor detection and discrimination in the mouse olfactory system. The $650,049 award will fund a 5-year project to investigate the structural determinants of odorant receptor (OR) activation and the translation of OR activation to neural signaling patterns...
This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), will support research by President and Fellows of Harvard College (doing business as Harvard Medical School) to investigate how olfactory sensory neurons adapt to different environments and how this impacts odor processing and perception. The $1,128,268 award, effective January 1, 2025 through May...
This federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), aims to investigate the cellular and molecular basis for how insects, specifically fruit flies, detect and respond to high osmolality (high concentration) in their food. The $194,375 award to the University of California, Santa Barbara will fund research over a 2-year period from May 1, 2025...
The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $129,142 project grant (CFDA 93.173 - Research Related to Deafness and Communication Disorders) to Florida State University (FSU) to investigate how temperature impacts salt taste perception and its neural processing in mice. The project aims to explore the behavioral and cortical effects of temperature on salt taste quality discrimination and intensity representation. This research is designed to provide a...
This federal Project Grant award, totaling $502,742.00 and provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), aims to uncover fundamental principles of sensory processing in the piriform cortex (PCX) of the mammalian brain. The research seeks to understand how the PCX encodes and represents olfactory information, with the goal of advancing knowledge of neural coding and...

This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173), will support research to define the spatial distribution and molecular characteristics of SOX10+ taste bud progenitor cells in the von Ebner's glands, as well as investigate the regulatory role of the SOX10 transcription factor in the differentiation of these progenitors into taste bud cells. The $377,681 award, with a project period from June 1, 2025 to March 31, 2027, will leverage advanced techniques such as inducible transgenic mouse lines, spatial transcriptomics, and CRISPR/Cas9 technology to achieve these research goals. The findings will enhance understanding of the maintenance of taste bud homeostasis and contribute to the field of communication disorders research.

Generated 6/17/25, 3:05 AM