Project Grant R21AG098252
- Federal Grant Award Summary The Medical College of Wisconsin, Inc. received a $429,000 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded February 1, 2026, with completion scheduled for January 31, 2028. This research project investigates the role of Chromosome 21 (HSA21) gene overexpression in aging-associated and amyloid-beta-induced neurodegeneration using Caenorhabditis elegans as a model organism. The research addresses...
- Federal Project Grant Award Summary The Medical College of Wisconsin, Inc. received a $441,460 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) for the period February 1, 2026 through January 31, 2028. The award supports biomedical research directed toward understanding cerebrovascular dysfunction in Alzheimer's disease and related dementias. The research project will utilize genetically modified rat models to investigate the role of the adapter...
- Federal Project Grant Award Summary Mentia DTX Inc. received a $505,561 project grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) effective July 1, 2025, through June 30, 2027. The award funds development of MentiaCompanion, an artificial intelligence-based empathic virtual companion system designed to track changing health states in persons living with Alzheimer's disease and related dementias (ADRD). The two-phase technology development project...
- Federal Grant Award Summary One Health Studio LLC received a $948,184 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded on September 20, 2025, with a completion date of September 19, 2026. The award supports the development and evaluation of the FLOURISH ALL platform, an artificial intelligence (AI)-enabled digital health solution designed to reduce Alzheimer's Disease and Alzheimer's Disease-Related Dementias (ADRD) risk in...
- Federal Project Grant Award Summary The Medical College of Wisconsin, Inc. received a $312,000 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective June 1, 2025 through May 31, 2027. This award supports research investigating the functional role of late-onset Alzheimer's disease (LOAD)-associated genetic variants in neurodegeneration and protein aggregation-induced neurotoxicity. The project utilizes Caenorhabditis elegans (C....
- Federal Grant Award Summary Brigham & Women's Hospital received a $3.69 million Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) awarded on September 15, 2025, with a completion date of September 14, 2029. The award funds development of specialized large language models (LLMs) designed to extract Alzheimer's disease and related dementias (ADRD)-relevant clinical phenotypes from electronic health records (EHRs). The project addresses a critical...
- Federal Grant Award Summary Boston University Medical Campus received a $327,000 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), awarded September 5, 2025, with completion scheduled for August 31, 2027. The grant supports research exploring heterogeneity of cognitive trajectories in preclinical Alzheimer's disease through digital phenotyping methodologies. The project leverages multimodal data integration, combining traditional...
- Federal Grant Award Summary The National Institute on Aging awarded the University of Washington a $2.21 million Project Grant on September 15, 2025, under the Aging Research program (CFDA 93.866) to develop and pilot an artificial intelligence-enhanced, culturally adapted version of STAR-C (Strategies to Reduce Behavioral and Psychological Symptoms Through Care) for Latino family caregivers of individuals with Alzheimer's disease and related dementias. The project, which extends through...
- Federal Grant Award Summary CareVirtue Technologies, Inc. received a $499,651 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) to develop an artificial intelligence-enabled dementia care agent designed to reduce caregiving disparities for rural Alzheimer's Disease and Related Dementia (ADRD) care partners. The award was obligated on September 20, 2025, with a completion date of September 19, 2026. The dementia care agent integrates a...
- Federal Grant Award Summary The University of Wisconsin-Milwaukee received a $293,454 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), effective January 15, 2026 through December 31, 2030. The award funds a three-experiment research project investigating the neural mechanisms underlying memory integration and generalization in aging adults. The research will employ functional magnetic resonance imaging (fMRI) with healthy young adults (ages...
The Medical College of Wisconsin, Inc. received a $195,000 project grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) effective June 1, 2026, with completion targeted for March 31, 2028. The award supports development and evaluation of a voice-activated and touchscreen-controlled (VATC) smart speaker intervention designed to improve diabetes self-management education (DSME) and behavioral skills training for adults aged 50 years and older with poorly controlled type 2 diabetes (T2DM). The intervention leverages artificial intelligence (AI) and personalized technology to deliver services in the home environment, addressing both clinical outcomes and unmet social needs such as food insecurity, transportation barriers, and social isolation that disproportionately affect older adults with diabetes. The smart speaker platform is designed to provide multiple services including DSME delivery, behavioral skills training, medication reminder scheduling, social needs assessment and referral, access to educational materials, and facilitation of family and friend interactions. By leveraging voice-activated and touchscreen technologies that bridge the digital divide, this intervention aims to help older adults with T2DM optimize hemoglobin A1C, blood pressure, and cholesterol control while supporting aging in place and reducing institutionalized care. The research is being conducted at the awardee's Wauwatosa, Wisconsin location and will generate evidence regarding the efficacy of AI-enabled technology interventions integrated with social care support for diabetes management in aging populations.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $195.0k | 6/3/26 |