Project Grant R01AG098263
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded University of Wisconsin-Madison a $640,906 Project Grant effective June 1, 2025, through March 31, 2030, under the Aging Research program (CFDA 93.866). The project delivers advanced neuroimaging research and analysis services focused on elucidating cerebrovascular disease (CVD) pathways to cognitive decline. The primary products include the development and application of a suite of non-invasive vascular neuroimaging tools...
- Federal Project Grant Award Summary The National Institute on Aging awarded The Washington University a $2.63 million Project Grant under the Aging Research program (CFDA 93.866) beginning September 1, 2025, with completion scheduled for August 31, 2029. This research initiative investigates age-related deficits in episodic memory for both content and structure of naturalistic events, with the objective of improving early detection of cognitive decline in at-risk older adults before...
- Federal Project Grant Award Summary The National Institute on Aging awarded a $749,108 Project Grant (CFDA 93.866, Aging Research program) to the University of California, Irvine on May 15, 2025, with a completion date of April 30, 2030. This R01 research award supports a computational and neurobiological investigation into memory-guided decision-making across the lifespan. The project will deliver scientific research products examining how different types of memory failures—including item...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded The Washington University a Project Grant totaling $1,851,569 under the Aging Research program (CFDA 93.866) for the period June 1, 2025, through March 31, 2030. This research initiative, titled "First In Last Out: How Development Informs Neurodegeneration," investigates the biological mechanisms linking early brain development to late-life Alzheimer's disease (AD) pathology. The project aims to empirically...
- Federal Grant Award Summary The Medical College of Wisconsin, Inc. received a $312,000 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective June 1, 2025, through May 31, 2027. The research project investigates the functional role of late-onset Alzheimer's disease (LOAD)-associated genes in neurodegeneration and protein aggregation-induced neurotoxicity. Using Caenorhabditis elegans as a model organism, the research aims to...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of California, Irvine $2.49M under the Aging Research program (CFDA 93.866) to conduct scientific research investigating circuit vulnerability in the entorhinal cortex during tauopathy-related Alzheimer's Disease (AD). The project, which commenced September 15, 2025, and extends through August 31, 2029, focuses on identifying neuronal cell types in the lateral and medial entorhinal cortex that are...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $412,500 Project Grant to the University of South Florida (USF) under the Aging Research program (CFDA 93.866) for a two-year research initiative running from June 1, 2025, through May 31, 2027. This grant funds scientific research aimed at identifying novel biomarkers for early diagnosis and prognosis prediction of Alzheimer's disease (AD), a neurodegenerative condition affecting 5.5 million Americans. The project...
- Federal Grant Award Summary The University of Washington received a $3.08 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective September 1, 2025 through August 31, 2029. This award funds the development of statistical machine learning methods to create connectome-based biomarkers for early detection of Alzheimer's disease and related dementias (ADRD). The project addresses critical gaps in current computational approaches...
- Federal Project Grant Award Summary The University of Texas at Austin received a $438,625 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded September 1, 2025, with completion targeted for August 31, 2027. The research initiative, titled "Decoding the Heterogeneity of Interneuron Vulnerability in Aging and Alzheimer's Disease: An Ultraplex CLEM Approach," will deliver comprehensive scientific investigation into age-related...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of Michigan $156,000 under the Aging Research program (CFDA 93.866) on August 5, 2025, with completion scheduled for April 30, 2027. This project grant funds a research initiative to map structural brain networks associated with mild behavioral impairment (MBI) in older adults during early-stage clinical phenotypes. The research leverages data from the National Alzheimer's Coordinating Center to...
The National Institute on Aging (NIA) awarded the University of Wisconsin-Milwaukee $293,454 under the Aging Research program (CFDA 93.866) to conduct a four-year research project from January 2026 through December 2030. The grant funds a comprehensive neuroscience study examining how advanced age affects memory integration—the cognitive ability to combine separate experiences and make inferences. Through three fMRI (functional magnetic resonance imaging) experiments, the research will measure neural and behavioral differences between healthy young adults (ages 18-30) and older adults (ages 65-80) as they perform inference tasks designed to probe memory integration at different cognitive stages: encoding, retrieval, and intermediate processing periods. The research deliverables will advance understanding of age-related changes in two key brain regions implicated in memory integration: the hippocampus and ventromedial prefrontal cortex (VMPFC). The project's primary aims include identifying age differences in neural systems supporting memory integration during learning, determining how older adults reactivate existing knowledge during new learning, and conducting whole-brain analyses to identify unique neural mechanisms that older adults recruit to maintain integration abilities. This research will contribute to resolving conflicting theories about cognitive aging and may inform strategies for improving decision-making and knowledge retention in older populations.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $293.5k | 1/14/26 |