Project Grant R21AG095422
- Federal Project Grant Award Summary Marquette University received a $309,000 project grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded on May 15, 2026, with a completion date of April 30, 2028. The project, "Longitudinal Imaging in a Preclinical Model of Alzheimer's Disease to Identify Early Biomarkers of Cognitive Decline," delivers longitudinal neuroimaging research and data analysis services aimed at understanding how ovarian...
- Federal Grant Award Summary The National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), awarded The Washington University a Project Grant of $326,550 effective June 15, 2026, through March 31, 2031. This award funds biomedical research directed toward understanding the neural circuit mechanisms underlying age-related changes in female social behavior, specifically addressing menopause-related depression, social withdrawal, and loss of sexual motivation. The research...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a Project Grant of $293,454 to the University of Wisconsin–Milwaukee, with an award date of January 15, 2026, and completion date of December 31, 2030, under the Aging Research program (CFDA 93.866). The research project investigates the neural mechanisms underlying memory generalization and integration in older adults through three fMRI-based experiments. The primary deliverables include behavioral and...
- Federal Grant Award Summary The National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), awarded the University of Michigan a Project Grant totaling $424,371 on February 15, 2026, with completion targeted for February 14, 2028. This award funds research investigating how lifetime estrogen exposure, particularly through hormone contraceptive (HC) use, protects against Alzheimer's disease (AD) progression in women. The primary deliverable is scientific research...
- Federal Project Grant Award Summary The University of Florida's Division of Sponsored Research received a $2.33 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective September 1, 2025, through August 31, 2029. The award funds research evaluating neuroimmune mechanisms and therapeutic targeting potential of the luteinizing hormone/chorionic gonadotropin (LH/CG) receptor in menopausal and Alzheimer's disease-affected brains....
- Federal Project Grant Award Summary Northwestern University's Sponsored Research Division received $198,164 in funding from the National Institute on Aging under the Aging Research program (CFDA 93.866) to conduct a project investigation titled "Investigating Sex-Specific Hypothalamic Pathology and Immune Infiltration in Alzheimer's Disease." The award, effective September 27, 2025, with completion targeted for May 31, 2028, supports research addressing the underexplored mechanisms...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded $174,672 to the University of California, Santa Barbara on March 18, 2026, under the Aging Research program (CFDA 93.866) to support research examining the influence of ovarian aging and endocrine shifts on spatial navigation as an early diagnostic target for Alzheimer's disease. The research project, scheduled for completion by September 20, 2026, investigates how ovarian hormones affect spatial navigation...
- Federal Grant Award Summary Brandeis University received a $142,997 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective October 16, 2025 through April 15, 2028. The award funds research investigating associations among monoamines, tau pathology, and emotional memory in aging populations. The research employs advanced positron emission tomography (PET) imaging methods, specifically [18F]fluoro-m-tyrosine ([18F]FMT) and [18F]MK-6240...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of Southern California $4,055,366 under the Aging Research program (CFDA 93.866) to conduct a four-year research project examining the impact of circulating endocrine disrupting toxicants on cognition, brain activity, and Alzheimer's disease (AD) biomarkers across the menopausal transition. The project, which commenced on September 15, 2025, and concludes August 31, 2029, addresses a critical gap...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded Magee-Womens Research Institute and Foundation a $681,020 Project Grant on June 15, 2026, under the Aging Research program (CFDA 93.866) to conduct biomedical research investigating the microbial regulation of type 2 immunity in ovarian tissue remodeling and fibrosis. The research will be conducted in Pittsburgh, Pennsylvania, with a completion date of February 28, 2031. The primary deliverables include scientific research...
Marquette University received a Project Grant award of $424,875 from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective June 15, 2026, with completion targeted for May 31, 2028. The award supports neuroscience research investigating how ovarian hormones and age influence the prefrontal cortex's encoding of episodic fear memories across the lifespan. The project employs in vivo miniscope calcium imaging technology to track neural activity in rats during fear memory acquisition, retention, and extinction phases. Research objectives include determining the contributions of estradiol and progesterone to fear memory encoding in young adult animals (Aim 1) and assessing how encoding patterns change with age in both sexes and whether hormone treatment in middle age alters memory decline trajectories (Aim 2). This research directly addresses NIA Strategic Goal 1 and aligns with Notice NOT-OD-24-079, which prioritizes health conditions predominantly affecting women. The anticipated outcomes include new understanding of how the prefrontal cortex encodes threat and threat-predictive cues across both sexes and the lifespan, with implications for improving health outcomes in aging populations experiencing menopause-related increases in affective disorders and Alzheimer's disease risk. The work is conducted at Marquette University's facilities in Wisconsin.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $424.9k | 6/8/26 |