Project Grant R21AG093397
Award Date 1/1/26
Completion Date 12/31/27
Dollars Obligated $429K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Colorado, USA
Similar Awards
- This $880,000 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will fund a study to examine the effects of daily stress, sleep, and sex hormones on accelerated vascular aging in premenopausal midlife women. The 2-year study, starting November 2024, will investigate how emotional reactivity to daily stressors and sleep variability contribute to vascular dysfunction prior to menopause, and how these factors interact with changes in estradiol levels. The...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports research to elucidate the molecular basis of sex-dependent differences in endothelial cell (EC) functions that may shape the outcomes of angiogenesis-driven diseases and aging. The $659,309 award, commencing on December 15, 2025 and concluding on November 30, 2030, will be carried out by the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. The research aims...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $184,464 to the University of Colorado to conduct a research project titled "Mitochondrial-Targeted Antioxidant Supplementation for Improving Cerebrovascular Function in Postmenopausal Women". The award, which runs from Sep 24, 2025 to Aug 31, 2030, aims to determine the efficacy of a mitochondrial-targeted antioxidant treatment for improving...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $161,000.00 to the University of California, Davis to investigate sex differences in atrial remodeling and arrhythmia risk in aging. The project will run from September 30, 2024 to August 31, 2026 and aims to advance the understanding of how biological sex impacts the development of atrial fibrillation, a common age-related heart condition. The research will leverage UC Davis's expertise in...
- The Project Grant award titled "Estrogen Modulation of Chondrocyte Mechanotransduction via Piezo1 and TRPV4" is funded by the National Institute on Aging (NIA) under the Aging Research Federal Grant Program (CFDA 93.866). The $451,000 award to The University of Texas Southwestern Medical Center supports research to investigate how biological sex and sex hormones, specifically estrogen, modulate the mechanotransduction of chondrocytes (cartilage cells) through the calcium-permeant...
- This federal Project Grant award of $416,625 from the National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), will support research at Saint Louis University (SLU) to investigate the effects of aging, sex, and hormonal status on atherosclerotic cardiovascular disease (CVD). The key objectives are to: 1) comprehensively map inflammatory cell profiles and cell-cell communication networks in atherosclerotic plaques of young and old male and female mice, including old...
- This federal Project Grant award for $349,728.00 from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research to identify cardiometabolic adaptations in male and female mice in response to acute and chronic exercise. The key objectives of the project are to: 1) Determine the time course of metabolic responses to acute exercise in male and female mice, 2) Identify adaptations in cardiac substrate utilization and metabolic pathways in response...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $429,394 to the University of Missouri System to target LARP6, an RNA-binding protein implicated in age-related cardiac fibrosis and heart failure with preserved ejection fraction (HFpEF). The research aims to utilize genetic and small molecule inhibitor models to disrupt the LARP6-collagen mRNA interaction, thereby preventing cardiac fibrosis and promoting pro-angiogenic signaling to improve...
- This Project Grant award in the amount of $116,710 was provided by the National Institute on Aging (CFDA 93.866 Aging Research) to the University of Connecticut to conduct research on sex-specific determinants of muscle quality in older adults. The goal of this career development award is to provide the principal investigator the necessary training, research experience, and preliminary data to establish themselves as a geriatric researcher specializing in interventions to improve muscle...
- This $163,145 Project Grant award was provided by the National Heart, Lung, and Blood Institute (NHLBI), a component of the National Institutes of Health, under the Cardiovascular Diseases Research program (CFDA 93.837). The grant supports research to investigate sex differences in cardiac macrophage response to pulmonary hypertension, a progressive and incurable cardiovascular disease that disproportionately affects women. The University of Colorado-Denver, the grant awardee, will conduct...