Project Grant R21AG086859

Award Date 8/1/24
Completion Date 7/31/26
Dollars Obligated $443K
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
College Park, MD 20742, USA
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  1. Measuring brain angiotensin peptides and peptidases in a genetically diverse Alzheimer's disease mouse model to understand the impact of susceptibility and resilience to late-onset Alzheimer's disease.

  2. Determining the effects of hypertension on the angiotensin peptide-peptidase profiles in early-onset susceptible mouse strains.

  3. Using bioinformatic tools to uncover connections between the brain angiotensin system and cognitive, cardiovascular, behavioral, sex-dependent, and neuropathological factors that may contribute to Alzheimer's disease risk and progression.

The University of Maryland, College Park has awarded a $76,959.00 sub-grant to George Washington University to support this research.

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