Project Grant R21AG085052

Award Date 8/1/24
Completion Date 7/31/27
Dollars Obligated $158K
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Cincinnati, OH 45221, USA
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This $192,737 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to Texas Tech University Health Sciences Center (TTUHSC) aims to investigate the mechanisms by which traumatic brain injury (TBI) leads to vascular and neuronal dysfunction, which can contribute to the development of age-related diseases. The key objectives are to determine: Whether inhibiting the interaction between prostaglandins and the biomarker UCHL1 can mitigate TBI-induced blood-brain...
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This federal Project Grant award, valued at $3,102,638.00 and spanning August 15, 2024 to July 31, 2027, was provided by the National Institute on Aging (CFDA 93.866 - Aging Research) to The Trustees of the University of Pennsylvania. The grant aims to develop novel gyrencephalic animal models that can recapitulate the complex neuropathological and clinical features associated with traumatic brain injury (TBI)-induced Alzheimer's disease and related dementias (ADRD). The project will evaluate...
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