This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program provides $274,855 to Mito-Biotherapeutics, Inc. to develop a novel fusion protein construct that can cross the blood-brain barrier and deliver a therapeutic payload to repair mitochondrial DNA damage in neurons following traumatic brain injury (TBI). The project aims to advance the understanding of bioenergetic dysfunction and its role in...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $453,860.00 to support research on the metabolic regulation of neutrophil extracellular traps (NETs) in traumatic brain injury (TBI). The 5-year project, beginning June 1, 2025 and ending April 30, 2030, aims to determine the role of AMPK modulation on functional outcomes and...
The University of Michigan was awarded a $721,867 Project Grant from the Department of the Army Medical Command under the Military Medical Research and Development federal grant program. The grant will fund research on Robust Neuroprotection with Noninvasive Near-Infrared Light: Translational Development of a Treatment for Traumatic Brain Injury from September 15, 2022 to September 14, 2025. The research aims to investigate medical solutions for traumatic brain injury on the battlefield by...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to the University of Cincinnati will investigate the role of mitochondrial dysfunction in the progression of Alzheimer's-like neurodegeneration following traumatic brain injury (TBI). The $158,247 award, with a performance period from August 1, 2024 to July 31, 2027, will support research to: 1) characterize injury-induced intracellular and extracellular changes in mitochondrial function and 2) elucidate...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $465,752 to the Regents of the University of Michigan - University of Michigan-Dearborn to conduct research on understanding cell chirality and cell-cell interactions at the neurovascular unit after traumatic brain injury. The key objectives are to: 1) Determine the...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $571,404.00 to the University of Pittsburgh to conduct research aimed at understanding and improving neurological outcomes after traumatic brain injury (TBI). The key research objectives are to: Evaluate the long-term therapeutic potential of an adiponectin receptor agonist in...
This federal Project Grant award, valued at $405,000.00 and granted by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research focused on understanding the effects of traumatic brain injury (TBI) on serotonin (5-HT) neurotransmission. The research aims to identify and characterize TBI-induced alterations in the transcriptional identity of specific...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, will fund research at the Augusta University Research Institute, Inc. (doing business as Georgia Health Sciences) to investigate the mechanisms linking traumatic brain injury (TBI) to subsequent neurodegeneration and dementia. The $1,975,262 award will support a 3-year study...
The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), awarded a $628,133 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to Rutgers, The State University in New Jersey. The grant, titled "METABOLIC MECHANISMS OF RECOVERY IN MILD TBI", aims to study the molecular mechanisms that mediate injury and protection from mild traumatic brain injury (mTBI) using rodent...
This federal Project Grant award of $2,217,454.00, awarded by the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420), supports a research study on the effects of transcranial photobiomodulation (PBM) in older adults with traumatic brain injury. The primary awardee is the Research Foundation of the City University of New York, which is collaborating with New York University School of Medicine as a sub-grantee. The research aims to...