Project Grant R15EY035473

Award Date 8/1/24
Completion Date 7/31/27
Dollars Obligated $414K
Federal Grant Program
93.867
Assistance Type
Project Grant
Place of Performance
Greeley, CO 80639, USA
Similar Awards
This Project Grant award from the National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), provides $237,996 to investigate groundbreaking approaches for in-vivo high-resolution imaging of fine corneal structures. The award aims to develop a speckle illumination holographic imaging system with polarization and phase-sensitive detection, enabling wide field-of-view and 3D imaging capabilities to overcome limitations of current corneal imaging techniques. If successful,...
This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) will support research to investigate the role of retinal signaling pathways in the development of myopia, or nearsightedness. The $391,250 award to Emory University will fund a 5-year study to quantify changes in on and off retinal pathways in myopic eyes, determine how disrupting the balance between these pathways impacts myopia susceptibility, and evaluate the influence of ambient light levels on this...
This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) provides $1,241,223 to the University of Pittsburgh to conduct research on the genetic and epigenetic circuits underlying retinal transcription programs and how perturbations in the retinal core regulatory networks lead to congenital vision disorders. The key objectives are to: 1) Use mouse models to dissect the molecular, cellular, and genomic effects of genetic mutations on retinal development; 2)...
This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) provides $146,922 to support research to understand the chromatin architectural landscape of retinal development at the single-cell level. The key objectives are to: 1) Capture 3D chromatin interactions of mouse retinal cells at key developmental stages using single-cell Hi-C (Aim 1); and 2) Identify changes in chromatin organization associated with retinal progenitor-specific loss-of-function of the NFI...
This Project Grant award from the National Eye Institute (NEI), under the federal Vision Research program (CFDA 93.867), provides $421,136 to the University of Maryland, College Park to develop advanced wavefront shaping techniques for improving optical imaging of the eye's posterior segment through ocular opacities. The research aims to demonstrate high-resolution fundus imaging behind cataracts, corneal opacities, and other vision-impairing conditions, which can currently limit access to...
This Project Grant award, funded by the National Eye Institute (NEI) under the Vision Research federal grant program (CFDA 93.867), supports a research project focused on understanding genetic and glial support mechanisms in acute and chronic models of photoreceptor degeneration. The total award amount is $385,000.00 over a 4-year period from August 1, 2025 to July 31, 2029. The project, led by researchers at Wayne State University, aims to compare the transcriptional, cellular, and functional...
This Project Grant award of $482,312.00 was provided by the National Eye Institute, under the federal Vision Research grant program (CFDA 93.867), to Trustees of Boston University. The project, titled "Testing a Dynamic Spatiotemporal Normalization Framework for Human Vision", will investigate how visual perception depends on both instantaneous input and temporal context, with a focus on understanding the role of normalization and temporal attention. The research will involve...
This Project Grant award of $517,600 from the National Eye Institute (NEI) under the Vision Research federal grant program (CFDA 93.867) supports research to investigate the interaction between visual signals that evoke eye fixation and optokinetic reflex in the retina. The research, to be conducted at Washington University, aims to gain new fundamental knowledge about the neural circuits and computational logic underlying the competition between central and peripheral vision. Using larval...
This Project Grant award from the National Eye Institute (NEI), under the federal Vision Research program (CFDA 93.867), provides $247,387 to Stanford University to establish a comprehensive strategy for recruiting, training, and retaining clinician-scientists in ophthalmology research. The overarching objectives are to educate and develop the next generation of clinician-scientists focused on vision-related diseases and disorders, and to enhance research capabilities within ophthalmology...
This Project Grant award from the National Eye Institute (NEI), under the federal Vision Research grant program (CFDA 93.867), will fund research to investigate how the gut microbiome impacts the development of the visual system. The $364,324 grant, awarded on Sep 1, 2024, will support a grantee at the University of Oregon to use a zebrafish model to study the specific cellular pathways and microbial products that mediate communication between the intestinal microbiome and the brain to influence...

This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) provides $413,920 to the University of Northern Colorado (UNC) to develop novel biophysical models of eye morphogenesis processes. Specifically, the project aims to:

  1. Create quantitative models of choroid fissure closure in zebrafish and foveal pit formation across species, testing the models against experimental data. This work will engage UNC undergraduate physics and biology students in all aspects of the research.

  2. Extend a "tension-based morphogenesis" model of cerebellar foliation to the developing retina to understand foveal shape development.

  3. Investigate elastic creasing instability as a potential mechanism of foveal pit formation through experiments and finite element simulations.

The project, running from August 2024 to July 2027, aligns with the NEI's mission to advance fundamental knowledge about living systems and supports the training of undergraduate researchers at UNC.

Generated 7/1/25, 2:32 AM