This $148,568 Project Grant award from the National Eye Institute (NEI), under the federal Vision Research program (CFDA 93.867), supports research at Emory University to investigate the role of scleral fibroblasts in refractive development and myopia. The primary objectives are to: 1) Identify characteristics of scleral fibroblasts in mouse eyes that undergo normal refractive development versus those exposed to myopic stimuli, and 2) Determine the role of retinoic acid signaling in driving...
This federal Project Grant award of $494,418.00 from the National Eye Institute (CFDA 93.867 - Vision Research) will support research to investigate the role of the visual environment in the development of myopia, or nearsightedness. The key objectives are: Determine the anti-myopia effectiveness of different real-world visual scenes to understand how the visual environment impacts eye growth and refractive development. Develop improved "repeated low-level red light" therapies that...
The National Eye Institute (NEI) awarded a $433,125 federal Project Grant (CFDA 93.867 - Vision Research) to The Ohio State University to leverage data from the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) study to address critical clinical questions in myopia control. The funded research aims to analyze axial length data to determine whom to treat and whether myopia control treatments are beneficial, assess the effects of time spent outdoors and sports...
This federal Project Grant award from the National Eye Institute (CFDA 93.867 Vision Research) provides $441,375.00 to The Regents of the University of California, Berkeley to explore pharmacological interventions for slowing the progression of myopia (nearsightedness) using a guinea pig animal model. The funded research will investigate the efficacy of topical treatments combining levodopa-carbidopa and atropine-levodopa-carbidopa in inhibiting defocus-induced myopia, and explore the underlying...
The National Eye Institute (NEI) awarded a Project Grant (CFDA 93.867 Vision Research) worth $210,534 to Legacy Emanuel Hospital & Health Center in Portland, Oregon. The grant, which runs from September 1, 2024 to August 31, 2026, will fund research to investigate the cellular, molecular, and structural alterations in the optic nerve head associated with the development and progression of juvenile myopia using a tree shrew model. Key objectives of the project include assessing changes in...
The National Eye Institute (NEI) awarded a $510,689 Project Grant under CFDA 93.867 (Vision Research) to the Georgia Tech Research Corporation. The grant, effective March 1, 2025 through February 28, 2030, will fund research to define the functional organization and retinotopic precision of top-down feedback circuitry from the anterior cingulate cortex to primary and higher visual cortical areas, as well as the functional organization and efficacy of these top-down feedback projections during...
The National Eye Institute (NEI) awarded a $388,750 Project Grant under the Vision Research program (CFDA 93.867) to The Washington University in St. Louis. The five-year grant, effective August 1, 2024, will fund research to investigate the role of the histone variant H3.3 in retinal cell fate specification and differentiation. The research aims to complete a full phenotypic characterization of retinal development upon loss of H3.3 from retinal progenitors and post-mitotic neurons, as well as...
The federal Project Grant award R21EY036536 was provided by the National Eye Institute (CFDA 93.867 Vision Research program) to the University of Alabama at Birmingham (UAB) to conduct a pilot study on using amber light exposure to slow myopia progression and axial eye elongation in children. The $816,750 award will fund a 2-year study to determine the efficacy of having myopic children wear amber-tinted contact lenses for up to 4 hours per day. The study aims to test the hypothesis that...
The National Eye Institute (NEI), under the U.S. Department of Health and Human Services, awarded a $606,092 Project Grant through the Vision Research program (CFDA 93.867) to The Regents of the University of California, doing business as the University of California, Berkeley (UC Berkeley). The grant, awarded on January 1, 2025, supports a 4-year research project to investigate the development of the preferred retinal locus (PRL) in individuals with central vision loss due to macular diseases...
The National Eye Institute (NEI), part of the National Institutes of Health, awarded a $252,573 Project Grant (CFDA 93.867 - Vision Research) to the Regents of the University of California, San Francisco (UCSF) for the "UCSF Program in Resident Opportunities for Mentored Ophthalmic Training in Experimentation (PROMOTE)" project. The program aims to recruit, train, mentor, and launch diverse resident-investigators with both clinical expertise and scientific, methodological, and...