Project Grant R01NS144825
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a Project Grant totaling $125,685 on August 9, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports research and development of a bioactive material intervention to address post-stroke dementia, a significant complication affecting approximately 7 million stroke...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a Project Grant totaling $122,526.00 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program on August 7, 2025. This two-year award, with a completion date of July 31, 2027, funds fundamental neuroscience research investigating the phase separation of neuronal pentraxins and their role in synapse...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a Project Grant of $423,500 on August 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. This two-year award, with completion scheduled for July 31, 2027, funds research investigating the mechanisms underlying cognitive dysfunction in neuromyelitis optica (NMO), a central nervous...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a project grant of $223,665 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) effective July 1, 2025, through June 30, 2030. Principal Investigator Dr. Rebecca Levy will conduct research to elucidate how CACNA1C gene variants cause interneuron pathophysiology and cortical network dysfunction. The...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a Project Grant totaling $499,516 (obligated February 1, 2026) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports the development of a novel imaging strategy to optimize brain tumor immunotherapy through creation of a first-in-class positron emission tomography (PET)...
- Federal Grant Award Summary The University of California, San Francisco (UCSF) received a $654,593 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective August 15, 2025 through July 31, 2030. This research project develops structure-guiding tools to investigate the role of choline transport in congenital hydrocephalus development. The...
- Federal Grant Award Summary The Leland Stanford Junior University received a $249,000 project grant from the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective August 1, 2025, through July 31, 2028. The award supports research to predict long-term neurodevelopmental outcomes in preterm infants through multimodal neuroimaging techniques and environmental factor analysis. The research integrates...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant totaling $122,526 to The Leland Stanford Junior University on May 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This research initiative, scheduled for completion by April 30, 2028, focuses on delineating Alzheimer's Disease (AD) initiation and propagation mechanisms using novel adult human...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a Project Grant totaling $209,177 (Award Date: February 1, 2026; Completion Date: January 31, 2031) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This research grant supports a five-year investigation into the MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4) pathway as a...
- Federal Grant Award Summary The Leland Stanford Junior University received a $424,234 Project Grant award dated May 16, 2025, from the National Institute of Neurological Disorders and Stroke under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports research into in vivo tracking of innate immune activation and therapeutic response in multiple sclerosis (MS) mouse models utilizing [18F]OP-801, a novel fourth-generation...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a Project Grant totaling $432,647.00 under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award, effective May 15, 2026, through April 30, 2031, supports fundamental research investigating ferroptosis as a cellular mechanism underlying post-hemorrhagic hydrocephalus in neonates with severe intraventricular hemorrhage (IVH). The research deliverables include experimental characterization of ferroptosis-driven ependymal and choroid plexus epithelial cell death using novel biomarkers and animal models, with specific aims to determine whether ferroptosis mediates cell death in ventricular tissues following severe neonatal IVH and to establish connections between ferroptosis activation and hydrocephalus development. The research work is conducted at Stanford's Palo Alto, California facility and employs innovative methodologies including a novel rat pup model of IVH, specialized ferroptosis biomarker detection (3R dimer of transferrin receptor 1), and genetic manipulation techniques using Belgrade rat models with DMT1 (divalent metal transporter 1) deficiency. The ultimate research objective is to advance preventive therapies for post-hemorrhagic hydrocephalus in preterm infants with severe IVH, addressing a significant unmet clinical need for which no current preventive treatments exist.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $432.6k | 5/19/26 |