Project Grant R21NS144835
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant of $1,375,478 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the J. David Gladstone Institutes in California. This grant funding supports a multidisciplinary research program to study the role of neurovascular dysfunction in neurodegeneration, CNS repair, and glial cell biology. Key research activities include in vivo two-photon and super-resolution...
- This $4,164,187 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to develop antigen-directed therapies for autoantibody associated neuroinflammatory diseases. The project aims to facilitate the discovery of autoantibodies directed to cell surface antigens, characterize their specificity, and generate recombinant human...
- This $198,928 Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The grant will support research at the University of California, San Francisco to elucidate the cellular mechanisms underlying central nervous system injury and progression in multiple sclerosis. Key objectives include determining the role of astrocyte response,...
- This $198,780 Project Grant, awarded by the National Institute of Neurological Disorders and Stroke (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders), will fund research conducted by the University of California, San Francisco to investigate the autoimmune mechanisms underlying vitamin B12 deficiency in the central nervous system. The grant aims to elucidate the molecular mechanisms by which autoantibodies inhibit cellular uptake of B12, understand...
- This federal Project Grant award of $654,287.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The goal of the project is to develop a computational model of neurocognitive impairment in multiple sclerosis (MS), focusing on updating the outdated framework used to characterize cognition in MS. The project aims to leverage cognitive psychology and...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on August 1, 2025 for $1,180,687. The purpose of this 8-year project is to investigate how neural stem cell niches transition from embryonic to postnatal stages in the human forebrain, with a focus on characterizing the different neural...
- This $375,659 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research conducted by Carnegie Mellon University to study interhemispheric coordination for memory and action. The research aims to advance the fundamental understanding of brain and nervous system structures, functions, and mechanisms related to neurological processes and...
- This $2,503,949 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at Rockefeller University aimed at discovering therapeutic targets for neurological diseases. The project utilizes new techniques and concepts to study the fundamental mechanisms of brain disorders, focusing on how differences in cell-specific RNA regulation contribute to...
- This federal Project Grant award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, consolidates multiple research projects into a single larger R35 grant to enable comprehensive exploration of biological mechanisms underlying neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Parkinson's disease. The...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $385,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Leland Stanford Junior University (Stanford University). This 2-year grant, effective February 1, 2025, will support the development of an inducible and multiplexed dual gene modulation CRISPR system to study neuronal activity and regeneration. The goal is to create a synthetic biology...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $423,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Leland Stanford Junior University (Stanford University) on August 1, 2025. The funding will support a research project titled "Defining Mechanisms of Cognitive Dysfunction in Central Nervous System Autoimmunity" through July 31, 2027. The project aims to evaluate the pathogenic role of the NMO-IgG antibody as a mediator of cognitive decline in patients with neuromyelitis optica (NMO), an autoimmune disorder affecting the central nervous system. The research will leverage data and biospecimens from two existing NMO patient cohorts to investigate the relationship between NMO-IgG, blood-brain barrier dysfunction, and patterns of cognitive impairment in this patient population.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $423.5k | 7/29/25 |