The National Institute of Mental Health (NIMH) awarded a $744,121 Project Grant (CFDA 93.242 - Mental Health Research Grants) to The Leland Stanford Junior University (Stanford University) to develop foundation models (FMs) specifically designed for large, open-source task-free fMRI datasets. The project aims to harness the transformative potential of FMs in the fields of clinical neuroscience and psychiatry to investigate multiple prevalent psychiatric disorders, predict clinical symptom...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program provides $769,352.00 to The Leland Stanford Junior University to develop an engineered bioprinting platform to study neural migration in brain assembloids. The goal is to create a more reproducible and physiologically-relevant in vitro model of interneuron migration for studying neurodevelopmental disorders. Key activities include evaluating...
The National Institute of Mental Health (NIMH) awarded a $1,453,943 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the University of California, Los Angeles (UCLA) for the period of June 1, 2025 to May 31, 2028. The grant will fund the development of an integrated, portable sensor suite to concurrently record neural activity, physiological arousal, motor signals, and physical interactions in social environments. The project aims to track neuro-behavioral attention...
This Project Grant award of $784,096.00 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to develop optimized methods for measuring brain excitability in depression. The key objectives are to: Investigate how adjusting transcranial magnetic stimulation (TMS) parameters affects neural activity measured with intracranial EEG. Optimize the TARGE"T" system to enhance short-latency TMS-evoked potentials...
The National Institute of Mental Health (NIMH) awarded a $422,280 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the University of Colorado-Denver. The 2-year grant, running from April 1, 2025 to March 31, 2027, will support research to identify and interrogate novel intracellular proteins that underlie the distinct nanoscopic architecture of the synaptic adhesion molecules neurexin-1 and neurexin-3. Specifically, the research will use advanced imaging...
The National Institute of Mental Health (NIMH) awarded a $1,401,862 Project Grant under the Mental Health Research Grants (CFDA 93.242) program to the University of California, Berkeley. The 5-year grant, which commenced on September 21, 2024, will support research to investigate the role of the orbitofrontal cortex (OFC) in inhibiting habitual responses in the striatum to enable goal-directed decision-making. The researchers will use a novel behavioral task and advanced neural recording...
This federal Project Grant award of $692,043 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to investigate the role of presynaptic homeostatic plasticity in mental health disorders such as autism and intellectual disability. The award recipient, The Regents of the University of California, San Francisco (UCSF), will conduct research to elucidate the molecular mechanisms underlying homeostatic plasticity and...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants (CFDA 93.242) program, provides $1,369,101 to the University of California, Los Angeles (UCLA) to conduct research on elucidating the regulation of cell fate specification in human cortical development. The goal is to better understand the etiology of neurodevelopmental disorders. The project will evaluate the signals that drive cortical arealization and laminar...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), is focused on studying the use of theta burst stimulation (TBS) to modulate hippocampal-cortical rhythms in patients with schizophrenia. The $160,272 award, effective June 1, 2025 through May 31, 2027, will support a combination of invasive and non-invasive brain stimulation experiments to investigate how TBS can influence hippocampal oscillations and...
This $120,015 Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants (CFDA 93.242) program, supports research by Harvard University to develop a novel technological pipeline that enables monitoring of large-scale neural activity in freely moving animals and identifies the transcriptomic identity of the same individual neurons. The research aims to understand the neural circuit mechanisms governing homeostatic, physiological, and social...