The National Institute of Mental Health (NIMH) awarded a $1,330,586 Project Grant under the Mental Health Research Grants (CFDA 93.242) program to The Leland Stanford Junior University. The grant, with a project period from September 1, 2024 to June 30, 2029, will fund research to investigate how changes in cerebrospinal fluid (CSF) potassium levels across brain development impact neural progenitor maintenance, neurogenesis, and brain physiology. The research aims to elucidate the role of...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program provides $769,352.00 to The Leland Stanford Junior University to develop an engineered bioprinting platform to study neural migration in brain assembloids. The goal is to create a more reproducible and physiologically-relevant in vitro model of interneuron migration for studying neurodevelopmental disorders. Key activities include evaluating...
The National Institute of Mental Health (NIMH) awarded a $156,656 Project Grant under the Mental Health Research Grants (CFDA 93.242) program to The General Hospital Corporation (doing business as Massachusetts General Hospital) to advance functional MRI (fMRI) techniques for mapping brain activity across cerebral cortical layers. The project aims to validate and benchmark a "linescan fMRI" method that can achieve higher spatial resolution than conventional laminar fMRI, enabling...
This Project Grant award of $784,096.00 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to develop optimized methods for measuring brain excitability in depression. The key objectives are to: Investigate how adjusting transcranial magnetic stimulation (TMS) parameters affects neural activity measured with intracranial EEG. Optimize the TARGE"T" system to enhance short-latency TMS-evoked potentials...
This federal Project Grant award of $1,920,113, awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports a research project titled "Narrowing the Mechanistic Gap for Anterior Prefrontal Cortex Function". The project aims to conduct a deep dive on the anatomy and function of the anterior lateral prefrontal cortex (ALPFC) region of the brain, which has been implicated in various mental health disorders such as...
The National Institute of Mental Health (NIMH) awarded a $1,453,943 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the University of California, Los Angeles (UCLA) for the period of June 1, 2025 to May 31, 2028. The grant will fund the development of an integrated, portable sensor suite to concurrently record neural activity, physiological arousal, motor signals, and physical interactions in social environments. The project aims to track neuro-behavioral attention...
This Project Grant award from the National Institute of Mental Health (NIMH) under CFDA Program 93.242 - Mental Health Research Grants is funding a $123,878 research project titled "Improving Statistical Power for Human Structural and Functional Connectomes" at Yale University. The project aims to investigate approaches to increase statistical power in studies examining brain connectivity, both through functional and structural connectomes, in order to improve the clinical relevance...
The National Institute of Mental Health (NIMH) awarded a Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Weill Medical College of Cornell University for $582,953. The project, titled "The KrackenCoder: A Multi-Modal Connectome Fusion Tool for Brain-Behavior Mapping," aims to create and validate computational tools that integrate and estimate multi-modal brain connectivity data across many individuals, with and without diagnoses, in a behaviorally relevant...
The National Institute of Mental Health (NIMH) awarded a $135,268 Project Grant (CFDA 93.242 - Mental Health Research Grants) to The Leland Stanford Junior University to leverage large language models and machine learning algorithms to assess depression and anxiety symptoms and risks for patients with cardiovascular disease or diabetes mellitus. The key products and services to be delivered under this four-year grant include: 1) Identifying symptomatic issues and care needs for depression and...
The National Institute of Mental Health (NIMH) awarded a $823,252 Project Grant (CFDA 93.242 - Mental Health Research Grants) to The Trustees of Princeton University on September 18, 2024. The grant will support a 5-year research project titled "CROSS-BRAIN, MULTI-REGION INTERACTIONS IN DECISION FORMATION AND DECISION COMMITMENT" that aims to enhance the understanding of the neural mechanisms underlying decision-making processes. The grant includes a $55,255 sub-award to The Johns...