This federal Project Grant award from the National Institute of Mental Health (NIMH), under their Mental Health Research Grants program (CFDA 93.242), provides $784,096 to The Leland Stanford Junior University (Stanford University) to conduct research aimed at improving depression treatment by establishing reliable markers of prefrontal cortex excitability. The project aims to investigate how adjusting transcranial magnetic stimulation (TMS) parameters affects neural activity, optimize a TMS-based method called TARGET to enhance measurement of early local TMS-evoked potentials, and test how these optimized measures can detect changes in prefrontal excitability induced by cognitive tasks and repetitive TMS treatment. The research is expected to characterize the neural effects of TMS parameter adjustments and develop efficient methods for assessing cortical excitability, which could enhance brain-based monitoring and facilitate personalized treatments for depression guided by cortical excitability measurements. The award period runs from May 1, 2025 to February 28, 2030.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $784.1k | 5/1/25 |