Project Grant R01HL176320
Award Date 9/10/25
Completion Date 6/30/30
Dollars Obligated $799K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Durham, NC 27701, USA
Similar Awards
- This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Federal Grant Program for Cardiovascular Diseases Research (CFDA 93.837), provides $123,104 to Emory University to conduct research on factors contributing to cardiovascular disease (CVD) comorbidities in persons living with HIV (PWH). The key objectives are to: 1) assess relationships between the metabolome, lipidome, HIV reservoir, and subclinical CVD, analyzing differences by sex; and 2) determine...
- The National Heart Lung and Blood Institute (NHLBI) awarded a $3,264,423 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to The Regents of the University of California, San Francisco (UCSF) to study the mechanisms underlying the increased risk of sudden cardiac death in people with HIV. The research aims to characterize the myocardial tissue effects of treated HIV, including immune activation, cardiac ion channel dysregulation, and region-specific arrhythmic...
- This federal Project Grant award of $2,981,544.00, awarded by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), will fund a study to assess the impact of asymptomatic cytomegalovirus (CMV) infection on cardiovascular event risk in people with treated HIV infection. The study will leverage data from a prior clinical trial of the CMV-specific antiviral drug letermovir and a case-cohort study of over 1,900 ART-suppressed people with HIV to...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) is funding research to discover novel biomarkers and biological mechanisms underlying early-stage heart failure (HF). The $147,486 award to Duke University will support the development of an automated computational phenotype to identify early-stage HF, which will then be applied to large population cohorts. The research aims to leverage multi-omics data integration and...
- This federal Project Grant award of $115,125.00 from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research to investigate the interaction between obstructive sleep apnea (OSA) and HIV infection on ventricular repolarization abnormalities. The research will be conducted by the University of Miami from February 1, 2025 to January 31, 2027. The goal is to delineate the independent and interactive effects of OSA and HIV on QT variability...
- The National Heart Lung and Blood Institute awarded a $145,419 Project Grant titled "Implementation Determinants and Community-Based Prevention for Cardiometabolic Disease in Mozambique: A Pilot Study" under the Cardiovascular Diseases Research program (CFDA 93.837). This award supports formative research to characterize determinants for effective implementation of integrated care for type 2 diabetes, hypertension, and HIV within ongoing health systems strengthening efforts in public...
- The Project Grant award titled "IPEDIHEART: INTERDISCIPLINARY RESEARCH TRAINING PROGRAM FOR PEDIATRIC HEART DISEASE" is funded by the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) for $200,938 from September 1, 2025 to August 31, 2030. The grant supports an interdisciplinary research training program at Duke University focused on advancing scientific understanding and treatment of pediatric and congenital heart diseases. The program aims to...
- This $275,196 federal Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research at the University of Chicago investigating the impact of adolescent reproductive health factors on the risk of cardiometabolic disease in young adult women. The project aims to analyze longitudinal data from the Pittsburgh Girls Study to examine associations between adolescent pubertal development, sexual health, and pregnancy history with...
- The National Heart Lung and Blood Institute (NHLBI), under CFDA Program 93.837 Cardiovascular Diseases Research, awarded a $3,519,835 Project Grant to the Scripps Research Institute in La Jolla, CA on September 5, 2025. The grant, titled "PLANB2CUREHIV (THE 'PLANB' CONSORTIUM) - PROJECT SUMMARY", aims to accelerate the preclinical development of safe and effective genome-edited B cell-based therapies that could provide long-lasting, broadly neutralizing antibody titers capable of...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $249,000 to support research focused on developing gene-edited primary human cells that can enhance HIV-1 resistance. The research aims to achieve greater than 90% deletion of the CCR5 co-receptor and up to 50% allelic knock-in of inhibitory peptides targeting viral fusion and uncoating, resulting in significant inhibition of both CCR5- and CXCR4-tropic HIV...