The National Heart, Lung, and Blood Institute (NHLBI) awarded a $162,728 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to the University of California, San Diego (UCSD) for a study focused on cardiovascular outcomes in patients with comorbid obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD), known as overlap syndrome (OVS). The 3-year project, running from January 1, 2025 to August 15, 2027, aims to evaluate the underlying...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), will support research to investigate the role of microglial glutaminase in HIV-induced sleep disturbances. The Johns Hopkins University, the awardee, will take the following steps: 1) characterize sleep phenotypes in two murine neurohIV models, 2) analyze microglia activation, neuronal activity, neuroinflammation, and microglial...
This Project Grant award of $133,410 from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) will support research to investigate the impact of sleep pathology on cardiac aging and cardiovascular disease risk. The project will leverage longitudinal sleep and cardiovascular health data from the Korean Genome and Epidemiology Study (KOGES) to assess how sleep apnea and sleep quality affect cardiac electrophysiological aging over a...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH), provides $641,960 in funding to Augusta University Research Institute, Inc. (doing business as Georgia Health Sciences) to investigate the mechanisms underlying the development of hypertension in people with HIV. The research, conducted under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), aims to determine how HIV-derived...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $123,104 to Emory University to conduct research on cardiovascular disease comorbidities in persons living with HIV (PWH). The research aims to: 1) assess relationships between metabolic profiles, HIV reservoirs, and subclinical cardiovascular disease by sex, and 2) determine sex-specific multi-omic signatures associated with increased...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $1,415,112 project grant under the Cardiovascular Diseases Research program (CFDA 93.837) to the Board of Regents of the University of Nebraska, through its University of Nebraska Medical Center (UNMC) division. The grant aims to evaluate a telehealth-delivered adaptive intervention to promote continuous positive airway pressure (CPAP) therapy adherence and improve health outcomes for adults newly diagnosed with obstructive sleep...
This federal Project Grant award of $1,405,336.00 was made on September 1, 2024 by the National Heart Lung and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The grant supports research at Florida International University (FIU) focused on understanding the pathophysiological mechanisms of HIV-associated chronic obstructive pulmonary disease (COPD). The key research objectives are to: 1) Identify how HIV Tat protein and cigarette smoke exposure alter the...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $740,271 to The Ohio State University to conduct research on the prevalence and under-diagnosis of obstructive sleep apnea (OSA) in primary care clinics. The key products and services to be delivered include: Determining the prevalence of OSA and its subtypes, as well as the rate of under-diagnosis, in primary care practices through...
This federal Project Grant award, with ID R01HL176283, was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The award provides $1,297,878.00 to the University of North Carolina at Chapel Hill to conduct research on HIV-associated lung disease, with a focus on understanding the role of nasal mucosal immunity and the microbiome. The key objectives of this 5-year project are to: 1) characterize the nasal immune...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $426,717 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to The University of Iowa to develop a novel 3D dynamic MRI (3D-DMRI) scheme capable of quantitatively characterizing upper airway collapse in patients with obstructive sleep apnea (OSA). The 5-year project aims to systematically validate the 3D-DMRI approach and assess its clinical utility in evaluating airway shaping and collapse patterns, both...