Project Grant R01HD123806
- The National Institute of Child Health and Human Development awarded Trustees of Tufts College $1.072 million on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate the mechanisms by which vaginal lactobacilli protect pregnancy outcomes. The research tests whether anti-inflammatory compounds produced by lactobacilli suppress inflammatory signaling that correlates with adverse pregnancy outcomes including preterm birth and reduced...
- The National Institute of Child Health and Human Development awarded Thomas Jefferson University $438,910 on August 17, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to develop and pilot a group-based well-child care model that integrates maternal healthcare for mothers with hypertensive disorders of pregnancy. The recipient will execute two primary aims. In Aim 1, the institution will conduct a user-centered design process including focus groups...
- The National Institute of Child Health and Human Development awarded The General Hospital Corporation (Massachusetts General Hospital) $443,954 on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a four-year mixed-methods assessment of obstetric readiness in low-resource emergency departments. The research addresses the clinical gap created by closures of labor and delivery units that leave 2.3 million women of childbearing age in...
- The National Institute of Child Health and Human Development awarded Women & Infants Hospital of Rhode Island $248,999 on May 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.HDR) to conduct a longitudinal study examining how maternal prenatal stress and nutrition intervention jointly influence child cognitive and neural development. The research leverages data from the ENAT trial, which randomized 2,390 pregnant women to receive enhanced nutrition...
- The National Institute of Child Health and Human Development, part of the Department of Health and Human Services National Institutes of Health, awarded $456,500 to The University of Texas Southwestern Medical Center on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award funds molecular characterization of human pregnancy-induced cervical epithelium through two research aims. First, the recipient will apply single-cell and spatial...
- The National Institute of Child Health and Human Development awarded Trustees of Tufts College (doing business as Tufts University School of Medicine) $453,750 on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate epigenetic inheritance of trauma effects through sperm microRNA changes. The research examines how trauma exposure in men correlates with altered microRNA profiles in sperm—specifically elevated levels of miRNAs 532, 361,...
- The National Institute of Child Health and Human Development awarded Massachusetts General Hospital $672,715 on June 18, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct the Metabolic Assessment of Metformin in Pregnancy (MOM-P) study. The award funds research to assess the physiological effects of metformin on maternal and neonatal metabolism during pregnancy in individuals developing gestational diabetes mellitus. The study examines...
- The National Institute of Child Health and Human Development awarded Vanderbilt University Medical Center $785,385 on September 2, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to evaluate the safety and efficacy of glucagon-like peptide-1 receptor agonists (semaglutide, liraglutide, tirzepatide) for pre-pregnancy weight management and pregnancy outcomes. The research leverages the National Patient Centered Clinical Research Network to conduct a...
- The National Institute of Child Health and Human Development awarded the University of Massachusetts Medical School $716,119 on July 25, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate dietary signaling mechanisms in male reproductive tissues and their epigenetic effects on offspring. The project explores how paternal dietary exposures influence cell composition and gene regulation in the testis, epididymis, and seminal vesicle, and...
- The National Institute of Child Health and Human Development awarded Vanderbilt University Medical Center $481,250 on September 1, 2026, under the Child Health and Human Development Extramural Research Projects program (CFDA 93.865, R21HD120973) to investigate associations between adverse pregnancy outcomes, severe maternal morbidity, maternal mortality, and cardiovascular events across women's complete reproductive histories. The recipient will assemble retrospective cohort studies combining...
The National Institute of Child Health and Human Development awarded Trustees of Tufts College (Tufts University School of Medicine) $740,405 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a randomized controlled trial testing medically tailored groceries as an intervention to improve pregnancy outcomes among food-insecure pregnant women. The trial will enroll 458 pregnant women with food insecurity, randomizing participants to receive either medically tailored, pregnancy-appropriate groceries paired with nutrition and culinary education, or enhanced standard-of-care control, from enrollment through six weeks postpartum. The primary outcome measures the effect of the intervention on a composite of nutrition-sensitive adverse pregnancy outcomes including hypertensive disorders of pregnancy, gestational diabetes mellitus, small-for-gestational-age, and large-for-gestational-age deliveries. Secondary outcomes include individual adverse pregnancy outcomes, gestational weight gain, and postpartum hypertension. The trial operates as a multi-site study with place of performance in Boston, Massachusetts. The award period runs from September 1, 2026, through May 31, 2031. This is a project grant, the assistance type for investigator-initiated biomedical research under the NICHD program.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $740.4k | 8/25/26 |