Project Grant R01HD121615
- Federal Project Grant Award Summary Boston Children's Hospital received a $674,620 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective September 1, 2025 through August 31, 2027. The award supports investigator-initiated research to elucidate the genetic and developmental basis for coordinated limb growth and proportion regulation. The research employs integrated...
- Federal Grant Award Summary Boston Children's Hospital received a $178,000 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective May 9, 2025, through April 30, 2027. The award funds research investigating the effects of maternal genetic risk factors for Polycystic Ovary Syndrome (PCOS) on birth and childhood outcomes in offspring. The research leverages...
- Federal Grant Award Summary Boston Children's Hospital received a $267,000 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective August 1, 2025, with completion anticipated by July 31, 2027. The award funds research to identify shared molecular mechanisms underlying congenital heart disease (CHD) and neurodevelopmental delay and disability (NDD) by characterizing dysregulated gene expression in...
- Federal Grant Award Summary Massachusetts General Hospital's Research Management Division received a $681,793 Project Grant award dated June 23, 2026, from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award supports research through March 31, 2031, focused on mapping the neuroarchitecture and connectivity development of the human cerebellum during the first year of postnatal...
- Federal Project Grant Award Summary Boston Children's Hospital received a $1.27 million Project Grant (R01) from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310), effective August 1, 2025 through July 31, 2027. The award supports collaborative research investigating the mechanisms through which transposable element (TE) mobilization and disrupted messenger RNA (mRNA) translation impair neural progenitor cell (NPC)...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded $356,000 to The Children's Hospital of Philadelphia Research Institute under the Child Health and Human Development Extramural Research program (CFDA 93.865) on May 15, 2026, with a completion date of April 30, 2028. This Project Grant funds research analyzing disease trajectories of rare genomic variants contributing to lesional brain disorders, specifically childhood epilepsies and brain...
- Federal Grant Award Summary Boston Children's Hospital has been awarded $1,155,809 under a Project Grant from the National Institute of Child Health and Human Development (NICHD) through the Child Health and Human Development Extramural Research program (CFDA 93.865), effective September 1, 2025, through May 31, 2030. The award funds the development of motion-robust magnetic resonance imaging (MRI) techniques to quantify iron levels in newborn brains, with particular focus on preterm infants...
- Federal Project Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded Massachusetts General Hospital $1.7 million under the Child Health and Human Development Extramural Research program (CFDA 93.865) on September 1, 2025, to validate and optimize non-invasive fetal sequencing (NIFS) technology for prenatal genetic screening. The award, extending through May 31, 2030, supports development of a high-resolution screening method capable of detecting...
- Federal Project Grant Award Summary Boston Children's Hospital received a $130,680 Project Grant award from the National Human Genome Research Institute (NHGRI) under the Human Genome Research program (CFDA 93.172), effective July 1, 2025 through June 30, 2027. The award supports the development of computational technologies and statistical methods for single-cell functional genomics analysis. The research deliverables include: (1) deep learning computational frameworks to decode epigenetic...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded Boston Children's Hospital a $1,991,224 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) effective September 1, 2025, through August 31, 2027. The award funds the development and implementation of TETRIS (Trends and Epidemiology Through Real-Time Injury Surveillance), a novel pediatric injury surveillance system utilizing...
Boston Children's Hospital has received a $431,781 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective July 1, 2026, through March 31, 2031. The award funds a mixed-methods research study investigating the broader impacts of genetic testing in individuals with cerebral palsy (CP), the most common childhood-onset motor disability in the United States. The research team will leverage an existing cohort of 250 CP patients who have undergone exome sequencing to characterize family perspectives on genetic testing utility, assess differences in neurodevelopmental outcomes and quality of life measures based on genetic diagnosis status, and analyze healthcare utilization patterns through electronic health record (EHR) data analysis. The project integrates quantitative and qualitative methodologies, including validated psychosocial impact instruments, semi-structured caregiver interviews, standardized neurodevelopmental assessments, structured EHR queries, and expert input through a modified Delphi process. This research addresses a critical gap in understanding how genetic diagnoses—identified in 20-30% of CP cases—influence clinical management, family psychosocial outcomes, and care pathways, with findings intended to inform the clinical utility of genetic testing for CP and inform best practices in pediatric neurodevelopmental care.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $431.8k | 6/23/26 |