Project Grant R56HD115763
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the CFDA Program 93.865 - Child Health and Human Development Extramural Research, is providing $386,100.00 to investigate the role of ectopic X-chromosome inactivation in limb patterning and development. The key objectives are to: 1) uncover the landscape of differentially suppressed genes through ectopic X-chromosome inactivation during limb development, and 2)...
- This federal Project Grant award, in the amount of $177,000.00, was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award supports research focused on understanding the genetic pathways that direct chondrocyte (cartilage cell) maturation and skeletal growth, with the goal of identifying novel modulators that could inform the development of treatments for...
- This federal Project Grant award of $185,388 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate how gene regulatory redundancy ensures developmental robustness in mammals. The primary objectives of the research are to: 1) Identify the distinct transcription factors driving each "shadow enhancer" (redundant regulatory DNA...
- This Project Grant award for $294,408 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 - Child Health and Human Development Extramural Research will support research to further understand how cell signaling mediates skeletal patterning during zebrafish fin regeneration. The research aims to identify Sonic Hedgehog (SHH) signaling target genes and elucidate how they promote interactions between SHH-expressing basal epidermal...
- This $451,000 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under CFDA Program 93.865 - Child Health and Human Development Extramural Research will support research to elucidate the role of the KBTBD2 gene in bone development and its relation to the genetic disorder Short Syndrome. The key objectives are to: 1) Determine the molecular mechanism by which KBTBD2 regulates bone development through its interaction with the p85a subunit of PI3K, a key...
- This federal Project Grant award of $760,617 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to understand the mechanisms underlying the transition of epiblast cells through different pluripotent states during peri-implantation development. The project aims to elucidate the molecular, cellular, and epigenetic events that occur during this...
- The Project Grant award of $157,500.00 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research at The Ohio State University to investigate the coordination of systemic and local signaling pathways that regulate proportional growth and body form development in Drosophila (fruit fly) wing discs. The award, spanning March 1, 2025 to February 28,...
- The Project Grant, awarded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), will fund a study to investigate how maternal hyperglycemia impacts embryonic metabolism and development in the C. elegans model. The $474,878 award will enable researchers at Childrens Hospital Medical Center to generate single-cell resolution data on metabolic changes during embryonic...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a 5-year, $164,160 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Children's Mercy Hospital in Kansas City, Missouri. The grant supports Dr. Gelineau-Morel's research to develop expertise in quantifying pharmacogenomic contributions to drug exposure, gain skills in physiologically-based pharmacokinetic (PBPK) modeling, and enhance...
- This $267,000 Project Grant awarded by the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research to advance the understanding of the connection between congenital heart disease (CHD) and neurodevelopmental disability (NDD). The grantee, The Children's Hospital Corporation (doing business as Boston Children's Hospital), will use human induced pluripotent stem cells (iPSCs) to (1) identify mechanisms by which syndromic CHD genes lead to...
This Project Grant award of $674,620 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) to The Children's Hospital Corporation (Boston Children's Hospital) supports research to understand the genetic and developmental basis for coordinated limb growth and proportion. The key research objectives include: This 2-year project aims to advance knowledge about the fundamental biological processes governing human development and limb growth, with the potential to improve understanding and treatment of genetic growth disorders.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $674.6k | 8/27/25 |