Project Grant R01HD120386
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) awarded a $426,346 Project Grant to the University of Maryland, College Park, effective May 10, 2026 through May 9, 2028. This research initiative investigates the direct effects of endocrine-disrupting chemicals (EDCs), specifically phthalates, on the vaginal microenvironment and their role in vaginal dysbiosis. The project addresses a significant...
- Federal Grant Award Summary The University of Cincinnati's Sponsored Research Services Division received a $450,811 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) for the period August 1, 2026 through July 31, 2028. The award supports research into the regulation and biological functions of Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1), a protein whose...
- Federal Grant Award Summary Midwestern University received a $521,992 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective September 1, 2025, through August 31, 2028. The grant supports research and career development activities investigating how phthalate exposure disrupts reproductive function through Liver Receptor Homolog-1 (LRH1) signaling pathways in Sertoli cells. The primary deliverables include...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) awarded the University of Illinois a Project Grant of $929,307 on February 18, 2026, with a completion date of January 31, 2034. This award funds research investigating the mechanisms by which endocrine-disrupting chemicals (EDCs) damage the ovary and impair female reproductive function. The research will employ advanced analytical and genomic...
- Federal Project Grant Award Summary Cincinnati Children's Hospital Medical Center received a $140,072 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective January 1, 2026, through July 20, 2028. The award funds research investigating the contribution of adipocyte (fat cell) inflammation to the timing of parturition, with particular focus on understanding mechanisms...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of North Carolina at Chapel Hill a $249,000 Project Grant under the Environmental Health program (CFDA 93.113) on September 12, 2025, for a three-year research initiative examining "Phthalates and Phthalate Alternatives and Early Human Cardiometabolic Development." The award supports investigation of associations between prenatal exposure to phthalates and phthalate...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Cincinnati a $459,770 Project Grant (CFDA 93.113 – Environmental Health) effective April 1, 2026, through March 31, 2028, to conduct research on microplastics exposure in house dust and its association with pediatric respiratory health outcomes. The primary deliverable is a quantitative and epidemiological assessment of microplastic concentrations, characterization by size,...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded $2.74 million under the Environmental Health program (CFDA 93.113) to the University of Illinois to investigate the neurodevelopmental impacts of phthalate exposure on social behavior circuits. The project, which commenced September 15, 2025, and will conclude September 14, 2029, will deliver comprehensive research examining how developmental exposure to phthalates—ubiquitous industrial...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded Michigan State University a $2.86 million Project Grant (CFDA 93.865, Child Health and Human Development Extramural Research) on September 12, 2025, to conduct transcriptomic research on early endometriotic lesion development. The five-year project, scheduled for completion by August 31, 2030, integrates single-cell, spatial, and bulk transcriptomics analyses of peritoneal endometriotic...
- Federal Grant Award Summary The University of Illinois received a $452,945 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded on September 8, 2025, with a completion date of August 31, 2027. This award funds research investigating how environmental chemical exposures modulate the ovarian lipidome and contribute to infertility. The project employs advanced matrix-assisted laser desorption/ionization...
The University of Cincinnati's Sponsored Research Services Division received a $696,598 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded July 15, 2026, with completion scheduled for May 31, 2031. The award funds research to investigate the role of environmental immunotoxicants—specifically phthalates including bis(2-ethylhexyl) phthalate (DEHP) and dibutyl phthalate (DBP)—in the development of endometriosis, a condition affecting approximately 10 million American women and costing the nation $100 billion annually. The research employs a mouse model of endometriosis to dissect mechanisms by which long-term phthalate exposure contributes to disease initiation and progression. The study will examine how these endocrine-disrupting chemicals enhance pro-inflammatory immune signaling, particularly interleukin 6 (IL-6) signaling and infiltration of innate immune cells such as neutrophils and macrophages during the critical 72-hour disease initiation window. Products from this research will include scientific findings and data elucidating the immunotoxicological mechanisms linking environmental chemical exposure to endometriosis development, advancing understanding of disease etiology and potentially informing prevention and clinical management strategies.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $696.6k | 7/10/26 |