Project Grant R21ES037063
- This $411,847 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program aims to investigate whether exposure to the neonicotinoid insecticide imidacloprid (IMI) leads to ovarian toxicity and female subfertility/infertility in mammals. The research will 1) determine the extent to which IMI causes ovarian toxicity and female reproductive impacts in a mouse model, and 2) identify IMI-induced changes in...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, provides $561,584 to Rutgers, The State University of New Jersey to study the ovarian disrupting effects of per- and polyfluoroalkyl substances (PFAS) on female reproductive health. The research aims to elucidate the mechanisms by which PFAS exposure, particularly perfluorononanoic acid (PFNA), interferes with ovarian...
- The University of Illinois was awarded a $626,812 Project Grant from the National Institutes of Health's National Institute of Environmental Health Sciences (CFDA 93.113 Environmental Health) to study cytoplasmic remodeling during the vertebrate oocyte-to-embryo transition. This 5-year research project aims to determine the role of endoplasmic reticulum (ER) remodeling, mRNA-ER association, and RNA phase transition as novel mechanisms underlying this critical reproductive process. The research...
- The University of Illinois was awarded a $108,512 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113). The grant, titled "LIPID-BASED INTERVENTIONS TO MITIGATE THE IMPACT OF ARSENIC ON MICROGLIAL FUNCTION AND NEUROBEHAVIOR", will fund research to investigate how the essential fatty acid docosahexaenoic acid (DHA) can protect against the neurobehavioral impacts of arsenic exposure. The...
- This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113) provides $521,992 in funding to Midwestern University to investigate how exposure to phthalates during critical developmental windows can disrupt spermatogenesis through the disruption of LRH1 signaling in Sertoli cells. The two-year project, running from September 1, 2025 to August 31, 2028, aims to elucidate the molecular...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a $143,331 Project Grant to Wayne State University to investigate the molecular impacts of per- and polyfluoroalkyl substances (PFAS) exposure on male reproductive health. The research aims to use single-cell RNA sequencing and analysis of epididymal extracellular vesicles to decipher how PFAS exposure affects spermatogenesis, sperm epigenetics, and overall...
- The University of Arizona received a $466,470 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), to investigate the impact of phthalate exposures on female reproduction and metabolism. The project aims to test the hypothesis that phthalate mixture exposure leads to stimulated fatty acid synthesis with concurrent inhibition of fatty acid oxidation, which may underlie the associations between...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), will provide $719,892 to New York University to conduct research on the relationship between infant exposure to phthalates and bisphenols and reproductive development during the "minipuberty" period in the first six months of life. The project will enroll 480 infants in the ongoing NYU Children's Health and Environment...
- This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), provides $124,728 to The Trustees of the University of Pennsylvania to conduct research on the impact of gestational and childhood exposure to endocrine-disrupting chemicals (EDCs) on adolescent neurobehavior. The key objectives of the research project are to: 1) assess the associations between gestational EDC exposure and...
- This Project Grant award, valued at $646,476.00, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113). The overarching goal of the research is to understand how environmental chemicals, such as inorganic arsenic, trigger deregulation of the epigenome that can resist epigenetic reprogramming in germ cells and become heritable. The award supports a study leveraging a model of germ cell reprogramming based...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), which is part of the Environmental Health federal grant program (CFDA 93.113), provides $452,945.00 to the University of Illinois to conduct research on the modulation of the ovarian lipidome by environmental exposures. The key objectives of the research project are to: 1) develop a spatial map of the human and mouse ovarian lipidome using mass spectrometry imaging techniques, and 2) investigate how exposure to organophosphate flame retardants (OPFRs) affects region-specific and lipid-specific changes in the ovarian lipidome. This research aims to improve the understanding of how environmental chemical exposures can lead to ovarian dysfunction and infertility. The award has an initial funding period from September 8, 2025 to August 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $452.9k | 9/6/25 |