Project Grant R15ES037124
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a $143,331 Project Grant to Wayne State University to investigate the molecular impacts of per- and polyfluoroalkyl substances (PFAS) exposure on male reproductive health. The research aims to use single-cell RNA sequencing and analysis of epididymal extracellular vesicles to decipher how PFAS exposure affects spermatogenesis, sperm epigenetics, and overall...
- The University of Arizona received a $466,470 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), to investigate the impact of phthalate exposures on female reproduction and metabolism. The project aims to test the hypothesis that phthalate mixture exposure leads to stimulated fatty acid synthesis with concurrent inhibition of fatty acid oxidation, which may underlie the associations between...
- The National Institute of Environmental Health Sciences (NIEHS) awarded a $2,737,859 Project Grant (CFDA 93.113, Environmental Health) to the University of Illinois to conduct research on the "Impacts of Phthalate Exposure on the Development of Social Behavior Circuits". The 4-year award, running from September 2025 to September 2029, aims to investigate how exposure to phthalates, a class of endocrine-disrupting chemicals, during development can lead to alterations in brain...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), will provide $719,892 to New York University to conduct research on the relationship between infant exposure to phthalates and bisphenols and reproductive development during the "minipuberty" period in the first six months of life. The project will enroll 480 infants in the ongoing NYU Children's Health and Environment...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a $2,472,661 Project Grant to the Texas A&M University System Health Science Center (TAMU HSC) to investigate the effects of phthalate exposure on epigenetic regulation of metabolic pathways and the development of metabolic diseases. The 4-year project, commencing on September 15, 2025, aims to elucidate the mechanisms by which phthalates, a group of...
- The National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) awarded a $1,999,075 Project Grant (CFDA 93.113 Environmental Health) to The Feinstein Institutes for Medical Research on September 1, 2023. The purpose of this 3-year grant is to investigate phthalate exposure and its mechanisms of action in the neonatal intensive care unit (NICU) environment. Specifically, the project aims to: 1) determine the pharmacokinetic profile of common phthalate...
- This Project Grant award, with a total funding amount of $249,000.00, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113). The award will fund a research study at the University of North Carolina at Chapel Hill investigating the associations between prenatal exposure to phthalates and phthalate alternatives and fetal and pediatric cardiometabolic outcomes. The study will utilize innovative tools to...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), which is part of the Environmental Health federal grant program (CFDA 93.113), provides $452,945.00 to the University of Illinois to conduct research on the modulation of the ovarian lipidome by environmental exposures. The key objectives of the research project are to: 1) develop a spatial map of the human and mouse ovarian lipidome using mass spectrometry imaging techniques, and 2) investigate how...
- This Project Grant award, valued at $646,476.00, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113). The overarching goal of the research is to understand how environmental chemicals, such as inorganic arsenic, trigger deregulation of the epigenome that can resist epigenetic reprogramming in germ cells and become heritable. The award supports a study leveraging a model of germ cell reprogramming based...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, provides $561,584 to Rutgers, The State University of New Jersey to study the ovarian disrupting effects of per- and polyfluoroalkyl substances (PFAS) on female reproductive health. The research aims to elucidate the mechanisms by which PFAS exposure, particularly perfluorononanoic acid (PFNA), interferes with ovarian...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113) provides $521,992 in funding to Midwestern University to investigate how exposure to phthalates during critical developmental windows can disrupt spermatogenesis through the disruption of LRH1 signaling in Sertoli cells. The two-year project, running from September 1, 2025 to August 31, 2028, aims to elucidate the molecular mechanisms by which phthalates impair germ cell development and determine the effects of phthalates on the functional capacities of mouse and human Sertoli cells. This research seeks to advance the understanding of how environmental exposures like phthalates influence reproductive health and fertility, with the goal of informing the development of targeted healthcare interventions. The award also supports career development activities for pre-doctoral health professionals and graduate students pursuing research in reproductive toxicology.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $522.0k | 8/28/25 |