This federal Project Grant award, with ID K99HD119028, was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The $114,458 award, with a performance period from August 1, 2025 to July 31, 2027, will support research at Duke University to quantitatively investigate how zebrafish appendage regeneration encodes and processes size memory at the cellular...
The Department of Health and Human Services (HHS) National Institutes of Health (NIH) awarded a $1,319,060 Project Grant to Duke University under the Trans-NIH Research Support (CFDA 93.310) program. The grant, effective September 1, 2023 through August 31, 2026, will fund research to study the robust formation of organs, with a focus on the development of the semicircular canals in the inner ear of zebrafish. The research aims to measure variations in tissue patterns, investigate the respective...
The federal Project Grant award R21HD116006 for $270,000.00, awarded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), will fund research to elucidate the cellular and molecular mechanisms enabling spinal cord regeneration in zebrafish. The primary objectives are to: 1) Analyze cell state changes over time associated with successful versus failed spinal cord...
This federal Project Grant award of $294,408, provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the role of Sonic Hedgehog signaling in regulating skeletal patterning during zebrafish fin regeneration. The research aims to identify key Sonic Hedgehog target genes and how they facilitate interactions between Sonic...
This federal Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $147,486.00 to investigate the role of the KIF2C gene in regulating the microtubule cytoskeleton during the oocyte-to-embryo transition in zebrafish. The award period is from September 1, 2025 to August 31, 2028. The research aims to determine how KIF2C modulates...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $955,521 to Yale University to conduct a cross-scale analysis of cell-extracellular matrix (ECM) adhesion in early spinal column development using zebrafish as a model organism. The project aims to quantify the molecular dynamics of single integrin heterodimers, which are the primary cell surface...
The National Institute of Child Health and Human Development (NICHD) awarded a $225,324 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Duke University to conduct research on the role of mitochondrial specialization in early embryonic development. The research, led by the Sherwood Lab, will utilize a newly developed in vivo toolkit in C. elegans to investigate how the mitochondrial electron transport chain (ETC) is regulated to meet the varying energetic...
This Project Grant award, valued at $107,458, was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant aims to investigate the mechanisms of double strand break repair in fetal male germ cells, which are precursors to spermatogonial stem cells that supply sperm throughout a male's reproductive lifespan. The research, to be conducted at Duke...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the federal Child Health and Human Development Extramural Research program (CFDA 93.865), provides $142,997 to the University Corporation at Monterey Bay to conduct research on the interaction between migrating cells and their substrate during tissue development. The key objectives are to investigate the role of BMP signaling in substrate morphogenesis driven by...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will provide $495,204 to The Trustees of the University of Pennsylvania to investigate the molecular basis for bone morphogenetic protein (BMP) receptor specialization and trafficking. The research aims to elucidate how specialized receptor functions and trafficking mechanisms fine-tune BMP signal transduction,...