This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 - Child Health and Human Development Extramural Research - supports a $142,996 research project at the University Corporation At Monterey Bay in California. The project aims to investigate the reciprocal influence between migrating cells and their substrate, specifically how cells in the caudal visceral mesoderm (CVM) nonautonomously modulate the directional growth of the trunk visceral mesoderm (TVM) through regulation of the bone morphogenetic protein (BMP) signaling pathway. The research will employ immunostaining and live imaging techniques to study the tissue-level interactions and signaling mechanisms underlying this phenomenon. The findings are expected to contribute to the understanding of how multiple tissue interactions guide proper patterning and development of organs, with implications for advancing knowledge in cell biology, developmental biology, and cancer metastasis. The award period is from April 1, 2025 to March 31, 2027.
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