Project Grant R01HD119172
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Icahn School of Medicine at Mount Sinai a $850,491 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective September 19, 2025, through August 31, 2030. This research initiative will conduct an in-depth characterization of myeloid cells in human milk from both HIV-negative and HIV-positive donors to elucidate their roles as potential vehicles for and...
- Federal Project Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded $249,000 to the Icahn School of Medicine at Mount Sinai under the Child Health and Human Development Extramural Research program (CFDA 93.865) on March 1, 2026, with completion targeted for February 28, 2029. This R00 Pathway to Independence Award establishes an independent research program for a tenure-track faculty member within the Departments of Psychiatry and Obstetrics,...
- Federal Grant Award Summary The National Institute of Child Health and Human Development awarded a $448,182 Project Grant to The Research Foundation For The State University Of New York (SUNY at Binghamton) under the Child Health and Human Development Extramural Research program (CFDA 93.865) for a project period from September 1, 2025 through March 31, 2027. The award funds the development of a novel physiologically based pharmacokinetic (PBPK) modeling approach to improve prediction of...
- Federal Project Grant Award Summary The National Institute of Child Health and Human Development awarded The Washington University a $119,544 Project Grant (CFDA 93.865: Child Health and Human Development Extramural Research) effective June 1, 2026, through May 31, 2028, to investigate the role of cell-free mitochondria in breast milk on neonatal metabolism and health outcomes. The research will deliver scientific knowledge regarding how maternal cell-free mitochondria, primarily derived from...
- Federal Grant Award Summary The University of Southern California received a $747,000 Project Grant awarded on August 1, 2025, from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The three-year project, extending through July 31, 2028, will conduct comprehensive research investigating the genetic and genomic influences on human milk composition and their impacts on infant health. The...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Icahn School of Medicine at Mount Sinai a $477,406 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective September 3, 2025, with completion targeted for August 31, 2027. The research aims to verify pigs as an appropriate animal model for developing human vaccines designed to elicit robust secretory immunoglobulin A (SIgA) responses in human breast...
- Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded The Regents of the University of Colorado—Denver $1,974,924 on July 24, 2025, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate the role of lipid droplet docking in lactation initiation and milk secretion. The project, extending through March 31, 2030, will deliver basic research findings aimed at understanding the cellular and molecular...
- Federal Grant Award Summary New York University School of Medicine received a $245,782 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective February 1, 2026, through January 31, 2029. The award funds a longitudinal research study examining how maternal immune activation (MIA) during pregnancy alters fetal and infant brain development during the critical birth...
- Federal Grant Award Summary Icahn School of Medicine at Mount Sinai received a $462,454 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310), effective August 8, 2025 through June 30, 2027. The award supports research investigating DNA methylation (5-methylcytosine) dynamics in Down syndrome (trisomy 21) hematopoiesis and leukemia development. The primary deliverable involves mapping epigenetic...
- Federal Project Grant Award Summary Loyola University of Chicago's Health Sciences Campus received a $519,054 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective September 10, 2025, with completion targeted for May 31, 2030. The award funds a randomized controlled trial investigating multisensory early oral administration of human milk (M-MILK) for very...
Icahn School of Medicine at Mount Sinai received a $751,204 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective June 1, 2026 through May 31, 2031. The award funds a comprehensive research investigation into the genetic and genomic mechanisms underlying human lactation disorders, including agalactia (complete absence of milk secretion) and hypogalactia (insufficient milk production). The research employs whole exome sequencing (WES) analysis to identify genetic variations and molecular mechanisms responsible for impaired milk production and secretion by comparing genomic data from women with lactation disorders against unaffected female controls. The project addresses a significant public health issue affecting approximately 40% of breastfeeding mothers, with implications for maternal well-being and child development, nutrition, and survival. By interrogating extensive health metadata alongside genomic data, the research aims to elucidate the inherited genetic components of lactation disorders and advance understanding of the biological pathways governing human milk production. The five-year initiative will generate scientific knowledge to inform clinical interventions and improve breastfeeding outcomes, particularly in underserved ethnic minority populations with lower breastfeeding initiation and support.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $751.2k | 5/26/26 |