This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under CFDA Program 93.865 Child Health and Human Development Extramural Research, aims to identify the molecular mechanisms linking lactation to metabolism. The $751,710.10 award, granted on August 15, 2024, will fund investigations to understand the effect of maternal gestational diabetes on mammary epithelial cell (MEC) progenitor insulin signaling and MEC profiles, as...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the federal Child Health and Human Development Extramural Research program (CFDA 93.865), provides $246,390 to Cornell University to conduct research on the molecular mechanisms regulating human milk production and composition. The research aims to elucidate physiological factors contributing to insufficient human milk production, a prevalent issue that leads to...
The National Institute of Child Health and Human Development (NICHD) awarded a $427,625 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to The Washington University in St. Louis, Missouri. The grant aims to provide a mechanistic understanding of how maternal obesity affects uterine contractility and energy metabolism during labor and parturition. The researchers will use a mouse model of diet-induced obesity to investigate the impacts of excess fatty acids...
The Joslin Diabetes Center, Inc. was awarded a $657,909 Project Grant by the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), to conduct research on the effects of maternal exercise during lactation on human milk composition and infant metabolism. The project aims to: 1) measure changes in thermogenic metabolites and lipids in human milk in response to acute and chronic maternal exercise;...
This $128,817 Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) to the Regents of the University of Minnesota supports a research project to comprehensively profile the composition of human breast milk and investigate its impacts on infant development. The project aims to identify genetic variants influencing milk metabolites, assess the effects of human cytomegalovirus reactivation in...
The National Institute of Child Health and Human Development (NICHD) awarded a $463,360 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Weill Medical College of Cornell University for a project titled "Maternal Milk Cytokines Activate Cognate Receptors in the Neonatal Esophagus to Program Adult Social Behavior." The research aims to determine how maternal milk cytokines interact with receptors in the neonatal esophagus to influence brain...
This $160,000 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under CFDA Program 93.865 - Child Health and Human Development Extramural Research supports research to understand fetal liver lipid metabolism under intrauterine growth restriction (IUGR) using a novel preeclampsia mouse model. The research aims to investigate the mechanisms linking IUGR to the development of adult non-alcoholic fatty liver disease (NAFLD), with a focus on the role of...
This $250,000 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) will support research at Colorado State University to investigate the role of maternal gut microbiome and inflammation in preeclampsia and subsequent cardiometabolic disease in offspring. The key research aims are to: 1) Determine if the maternal gut microbiome contributes to pro- or anti-inflammatory short-chain fatty acid signaling at the...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $1,600,000 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the Icahn School of Medicine at Mount Sinai. The project, titled "Decoding Endocrine and Paracrine Communication Through Mammokines," aims to discover new signaling molecules from the mammary gland that influence metabolic function and the progression of obesity and type 2...
The University of Colorado-Denver received a $2,137,104 Project Grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant will fund a comprehensive research study titled "Massachusetts Outcomes Study of Assisted Reproductive Technology Equity" from September 2024 through May 2029. The study aims to investigate racial/ethnic disparities in...