Project Grant R01HD118022
Award Date
6/1/25
Completion Date
5/31/30
Dollars Obligated
$661K
Federal Agency
National Institute of Child Health and Human Development
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Michigan, USA
Similar Awards
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the federal Child Health and Human Development Extramural Research program (CFDA 93.865), provides $624,000 to the Regents of the University of Michigan to investigate the impact of obesity and adiposity on the human endometrium. The primary objectives are to: 1) Perform single-nuclear RNA sequencing on endometrial samples from women with and without obesity to understand how pathologic...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $601,499 to The Trustees of the University of Pennsylvania to conduct research on how maternal obesity alters mitochondrial function in offspring and leads to the development of obesity and metabolic syndrome later in life. The key research objectives are to: 1) determine if the transfer of...
This $448,441 federal Project Grant awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support research at Emory University to investigate the role of mediobasal hypothalamic gliosis in gestational weight gain and visceral fat accretion. The primary aim is to provide foundational data on a potential neural mechanism underlying dysregulated or pathological weight gain during...
This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research program) provides $2,163,115 in funding to The University of Texas Health Science Center at San Antonio to conduct research aimed at disentangling the genetic mechanisms of endometriosis severity using single-cell multi-omics approaches. The research project, scheduled to run from September 1, 2024 to May 31, 2029, will involve...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $595,858 in funding to the Regents of the University of Michigan to conduct research on the role of hypothalamic SH2B1 neurocircuits and SH2B1 signal transduction pathways in obesity and metabolic disease. The research aims to: 1) determine whether specific neurocircuits between...
This Project Grant award for $1,538,070.00 was provided by the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865). The funding will support research at the University of Minnesota to investigate the role of mitochondrial nutrient transport in regulating trophoblast (placental) cell differentiation. The research aims to define the mechanisms by which glucose and glutamine metabolism through the...
This federal Project Grant award, totaling $456,251.00, was provided by the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865). The overarching goal of the proposed research is to test the hypothesis that pro-inflammatory mediators produced by maternal adipose tissue (leptin) reduce pro-angiogenic immune cells and factors at the maternal-fetal interface, which can contribute to adverse pregnancy outcomes...
The National Institute of Child Health and Human Development (NICHD) awarded a $427,625 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to The Washington University in St. Louis, Missouri. The grant aims to provide a mechanistic understanding of how maternal obesity affects uterine contractility and energy metabolism during labor and parturition. The researchers will use a mouse model of diet-induced obesity to investigate the impacts of excess fatty acids...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $231,708 to support research on the implications of iron homeostasis and ferroptosis in early pregnancy and endometriosis. The research aims to investigate how dysregulation of the iron export protein SLC40A1 (ferroportin) contributes to elevated oxidative stress and compromised decidualization...
This federal Project Grant award, totaling $1,026,038.00, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports research to investigate the molecular mechanisms by which oocyte mitochondrial activity regulates embryo telomere reprogramming, a key process that determines offspring aging and lifespan. The research aims to define how maternal obesity and...