This federal Project Grant award, issued by the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 (Child Health and Human Development Extramural Research), is providing $752,491 in funding to Kent State University from April 1, 2025 through December 31, 2029. The purpose of this award is to support research on the neural circuits mediating pulsatile and surge secretion of gonadotropin-releasing hormone (GnRH), which is critically important for female fertility. The research will focus on testing the hypothesis that specific subpopulations of neurons in the arcuate nucleus of the hypothalamus, including those expressing Kiss1r, play a key role in driving episodic and surge GnRH secretion. This research in sheep, an animal model closely resembling human reproductive physiology, aims to further refine understanding of the neural systems responsible for regulating GnRH release, with potential clinical relevance for reproductive disorders like polycystic ovarian syndrome.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $752.5k | 4/1/25 |