Project Grant R01HD111948

Award Date 7/22/24
Completion Date 5/31/29
Dollars Obligated $1.7M
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Pullman, WA 99164, USA
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The purpose of this grant is to investigate the impact of maternal obesity and maternal exercise on hippocampal synapse formation and development, and the role of key metabolic hormones such as insulin, apelin, and irisin in mediating these effects. The research aims to determine how maternal metabolic state can positively or negatively influence brain development and function, with the goal of informing strategies to mitigate cognitive and emotional disorders. The project will involve a series of in vivo studies to elucidate the underlying molecular mechanisms linking maternal metabolic factors to synaptic development in the hippocampus.

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