This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $243,750 to The Trustees of the University of Pennsylvania to conduct research on the maternal regulation of microtubules in vertebrate egg developmental competency. The key objectives are to investigate the dynamics, etiology, and nature of the spindle-like microtubule and vesicle-like structures in zebrafish eggs, as well...
This federal Project Grant award, with an ID of R01HD117197, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The $657,909 award will support a study to examine the effects of maternal exercise during lactation on human milk composition and its impact on infant metabolism and body composition. The key objectives are to: 1) Measure changes in thermogenic metabolites and...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to examine the effects of government-led cash transfer programs on health outcomes among women and young children in low- and middle-income countries. Using data from 37 countries, the $325,000 award will fund a longitudinal study to assess the impact of these programs on mortality rates, with a...
This federal Project Grant award of $1,026,038 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the molecular mechanisms by which maternal obesity impacts embryo telomere reprogramming. The key products and services to be delivered through this award include: Defining the molecular pathways by which oocyte mitochondrial activity regulates embryo...
The National Institute of Child Health and Human Development (NICHD) awarded a $147,486 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Trustees of the University of Pennsylvania. The grant, with a project period from September 1, 2025 to August 31, 2028, will fund research to investigate the role of the protein KIF2C in regulating the microtubule cytoskeleton during the oocyte-to-embryo transition. Key objectives include determining...
This federal Project Grant award, funded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to utilize the NHANES-linked Medicaid data to understand the role of preconception lifestyle factors on pregnancy outcomes. The $1,332,733 award, with a project period from September 2024 to May 2028, will support an innovative approach to examine the impact of preconception exposures, such as...
This federal Project Grant award of $414,026, provided by the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 - Child Health and Human Development Extramural Research, will support research to determine the mechanism by which maternal interleukin-10 (IL-10) restricts fetal emergency myelopoiesis, with the goal of improving neonatal outcomes. The research, conducted by Childrens Hospital Medical Center in Cincinnati, Ohio, aims to: 1) identify the...
This $1,454,109 Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to understand the genetic and physiological mechanisms by which the placenta adapts to hypoxia (low oxygen) and the implications for fetal growth and development. The research aims to 1) characterize how individual placental cell type responses to hypoxia contribute to...
This federal Project Grant award, funded by the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 - Child Health and Human Development Extramural Research, will support research to elucidate the neighborhood- and individual-level factors associated with pregnancy glycemia levels and childhood obesity risk. The $272,700 award, with a period of performance from August 1, 2024 to July 31, 2026, will enable the principal investigator to conduct a two-phase research...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $1,667,788 in funding to Washington State University (WSU) to conduct research on the effects of maternal obesity and exercise on hippocampal synapse development and its implications for mental health disorders. The research aims to determine how maternal insulin, apelin, irisin, and BDNF...