This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will provide $642,343 to American University to conduct research on the effects of federal funding for obesity prevention programs on weight-related health behaviors, obesity prevalence, and obesity-related chronic conditions. The project will leverage variation in which counties and...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $695,295.00 to study the developmental trajectories of reinforcer pathology and childhood obesity. The project will assess how the reinforcing value of food and physical activity, as well as delay discounting, change throughout childhood and adolescence, and how these...
This $499,761 federal Project Grant award, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research conducted by the Albert Einstein College of Medicine in Bronx, NY. The award aims to define the connectivity between hypothalamic melanocortin peptide-expressing neurons and melanocortin 4 receptor (MC4R)-expressing neurons in the medial prefrontal...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $789,350 to The Pennsylvania State University (Penn State) to investigate biological mechanisms linking early-life adversity, such as child maltreatment, with obesity risk in a high-risk pediatric cohort. The 5-year research project aims to elucidate the cross-sectional and...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $136,449 project grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The Regents of the University of California, Berkeley. The award, which runs from December 1, 2024 to November 30, 2026, will fund research to optimize the use of CRISPR-mediated gene downregulation to rapidly test whether genes linked to human obesity are required for the function of...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $176,500.00 to the University of Washington to investigate the links between hypothalamic microglia activation and perineuronal net (PNN) loss in the arcuate nucleus, and how these changes contribute to the pathogenesis of diet-induced obesity and glucose regulation. The...
This federal Project Grant award of $1,600,000 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research at Beth Israel Deaconess Medical Center, Inc. (BIDMC) to develop a computational pharmacology approach for coordinating the regulation of multiple neuron types related to energy balance and satiety. The research aims to identify combinations of 2-10 ligands...
The federal Project Grant award R01DK141559 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The $1,280,753 award, effective December 1, 2024 through November 30, 2029, supports research to investigate the role of hypothalamic SH2B1 neurocircuits and SH2B1 signal transduction pathways in obesity and metabolic disease. The research aims to determine how...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $1,428,186.00 to Beth Israel Deaconess Medical Center, Inc. (BIDMC) to conduct research on the role of CYP4F enzymes in regulating N-acyl amino acid signaling in humans. The project aims to biochemically characterize N-acyl amino acids as substrates and inhibitors of CYP4F...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $1,600,000 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the Icahn School of Medicine at Mount Sinai. The project, titled "Decoding Endocrine and Paracrine Communication Through Mammokines," aims to discover new signaling molecules from the mammary gland that influence metabolic function and the progression of obesity and type 2...