This $421,600 Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) will support research at Tufts Medical Center in Boston, MA to investigate the regulatory mechanisms governing retinal neovascularization. The research aims to delineate the role of chemokine signaling in recruiting peripheral immune cells to facilitate pathological vascular growth, as well as the role of microglial complement receptors in regulating neovessel regression. The project will utilize innovative techniques such as multiplex in-situ hybridization, cell-specific mRNA sequencing, and genetic mouse models. The award has an initial project period from August 1, 2024 to July 31, 2029, with the goal of advancing the understanding of innate immune regulation of retinal neovascularization and identifying new or improved treatment strategies for proliferative retinopathies.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $421.6k | 7/22/24 |