This $670,496 Project Grant award from the National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), supports research to investigate the paradoxical role of anti-VEGF therapy in subretinal fibrosis (SRF) associated with neovascular age-related macular degeneration (NAMD). The project aims to elucidate the mechanisms by which anti-VEGF therapy at different disease stages impacts SRF, and to develop novel dual anti-angiogenesis and anti-fibrosis therapies. The research will be conducted by Baylor College of Medicine, a private non-profit health sciences university, over the period from Sep 1, 2024 to May 31, 2028. The successful implementation of this project is expected to confirm the causal link between anti-VEGF therapy and SRF, and provide a clinical strategy to mitigate the emerging epidemic of anti-VEGF-induced SRF in NAMD patients.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $670.5k | 8/16/24 |