Project Grant R01DK138972
Award Date
1/20/25
Completion Date
11/30/28
Dollars Obligated
$684K
Awardee
Duke University (TP7EK8DZV6N5)
Federal Grant Program
93.847
Assistance Type
Project Grant
Place of Performance
North Carolina, USA
Similar Awards
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is supporting the development of a novel noninvasive ultrasound-based treatment called Burst Wave Lithotripsy (BWL) to safely fragment large kidney stones. The $278,224 award to Sonomotion Inc. aims to expand the BWL technology to treat stones in the 10-20 mm range, addressing the high...
This federal Project Grant award in the amount of $1,592,381.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) is for the creation of the Urinary Stone Disease Hub (USDHUB), a comprehensive research resource to support a wide range of clinical investigations on urinary stone disease. The USDHUB will generate a cohort of over 230,000 individuals across the lifespan...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $434,502 to The Medical College of Wisconsin, Inc. to investigate the protein interactions that control calcium oxalate kidney stone formation. The goal of the research is to understand the mechanisms by which a complex mixture of proteins, including strongly anionic, strongly...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research) totaling $249,951 aims to develop a novel targeted ablation tool called BACTVUE for managing antibiotic-refractory recurrent urinary tract infections (UTIs). The project, conducted by the University of Texas at Dallas, has two primary goals: 1) to demonstrate BACTVUE's ability to selectively stain diverse intracellular...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to leverage a unique dog model to investigate the role of the protein uromodulin in kidney stone disease. The $368,500 award, effective September 1, 2024 through August 31, 2025, will support research to identify how defects in uromodulin polymerization and peptide excretion impact renal...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will fund a clinical study to determine the feasibility and potential efficacy of using pulsed ultrasound stimulation to reduce inflammation and prevent acute kidney injury (AKI). The $311,538 award, effective September 15, 2024 through August 31, 2027, will support two main objectives: 1) Testing...
This $268,377 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is funding the development and validation of a novel device utilizing high-frequency, low-amplitude vibration (HFLAV) to accelerate the healing of Stage 2 diabetic foot ulcers (DFUs). The primary objectives are to: 1) Enhance and validate the HFLAV driver device by incorporating...
This $337,284 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will support the development of a novel "Precision-Cut Bladder Slice" (PCBS) technology at Boston Children's Hospital. The goal is to enable quantitative assessment of bladder smooth muscle contraction, relaxation, and stiffness in both healthy murine and human tissues, while...
This Project Grant award, valued at $629,250.00, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research to examine the role of hyaluronic acid (HA) in the pathobiology of benign prostatic hyperplasia (BPH) and associated lower urinary tract symptoms (LUTS). The primary objectives are to characterize the relationship between HA,...
This Project Grant award from the National Center for Advancing Translational Sciences (NCATS) under CFDA Program 93.350 provides funding of $437,761 to the University of Texas at Austin for a 2-year research project from August 2024 to July 2026. The project aims to determine if a human enzyme therapeutic that degrades cystine can prevent or slow the formation of cystine kidney stones and mitigate associated kidney pathology in a mouse model of cystinuria, a rare metabolic disorder causing...