Project Grant R01DA063125
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the Regents of the University of Michigan a Project Grant totaling $170,744 on June 17, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279) to support basic neuroscience research investigating the glucocorticoid receptor (GR) as a regulatory mechanism underlying inhibitory control deficits associated with substance use disorder. The research will examine the top-down neural pathway connecting the...
- Federal Project Grant Award Summary New York University has been awarded $201,250 by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) for a two-year project period from June 1, 2025, through May 31, 2027. This Project Grant supports basic neuroscience research investigating the synaptic organization of cholinergic interneurons in the nucleus accumbens, a brain region critical to motivated behaviors and implicated in substance use...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded The Johns Hopkins University a $1.9M Project Grant on July 15, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct basic neuroscience research examining the neural mechanisms underlying the transition from goal-directed to habitual behavior. The research extends through March 31, 2030, and will be conducted at the institution's Baltimore, Maryland facility. The project develops and...
- Federal Grant Award Summary Northwestern University received a $161,517 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning September 1, 2025, through August 31, 2030. The Substance Use Research Training Program for Physician Researchers in Emergency Medicine (SUPR-EM) provides structured research training and career development support for emergency medicine residents pursuing academic careers in...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded $107,090 to the University of Maryland, College Park on February 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279). This 24-month project grant supports longitudinal research investigating how perinatal substance use (PSU) and perinatal depression (PD) trajectories impact neonatal brain development. The research will model the interplay between PSU and PD using person-centered,...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded $781,032 to The Research Foundation for the State University of New York on August 1, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279) to support a project titled "Interplay Between Limbic Norepinephrine and Dopamine Circuits in Sex Differences in Reward and Aversion." The research project, which extends through April 30, 2030, will be conducted at the University at Buffalo,...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded The Johns Hopkins University a Project Grant (R21) totaling $439,180 under the Drug Use and Addiction Research Programs (CFDA 93.279) for the period September 1, 2025 through August 31, 2027. This high-risk/reward research initiative investigates dopaminergic neuronal-glial interactions in the striatum to advance understanding of cognitive dysfunction and chronic pain experienced by people living with HIV (PLWH)...
- Federal Project Grant Award Summary New York University received a $390,687 Project Grant from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) effective August 1, 2025, with completion scheduled for April 30, 2030. This award supports neuroscience research investigating how multiregional brain interactions support value-based decision-making and belief updating relevant to addiction-related behaviors. The research focuses on characterizing...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a $811,112 Project Grant to the Regents of the University of California, San Francisco effective July 1, 2025 through March 31, 2030 under the Drug Use and Addiction Research Programs (CFDA 93.279). This neuroscience research project investigates the network and circuit dynamics supporting dopaminergic control of sudden insight learning in cue-reward associations. The research combines advanced neuroimaging...
- Federal Project Grant Award Summary The Lieber Institute for Brain Development received a $1.86 million Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded March 1, 2026, with completion targeted for February 28, 2029. The institute will deliver a comprehensive three-dimensional cellular resolution spatio-molecular map of the human nucleus accumbens (NAC), a critical brain region implicated in reward signaling...
Northwestern University's Sponsored Research Division received a $722,218 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded March 1, 2026, with completion targeted for December 31, 2030. The research project, conducted at the awardee's Chicago, Illinois facility, investigates the effects of developmental environment on dopamine circuit structure and function, with emphasis on understanding how early life stress produces long-lasting impacts on neuropsychiatric outcomes including addiction and depression. The research deliverables encompass a systematic, multi-phase investigation utilizing mice as a model system to isolate the mechanisms by which early life stress permanently alters dopamine circuit development and function. Specific research products include: spatial transcriptomic analyses characterizing gene expression changes in midbrain dopaminergic cell types across development (Aim 1); anatomical and connectivity studies examining dopamine neurite complexity and structural consequences of stress-induced gene expression changes (Aim 2); and functional assays measuring informational content of dopamine signals to downstream striatal regions (Aim 3). The research integrates gene expression data, circuit anatomy, functional measurements, and computational analyses to elucidate how transient developmental experiences produce lasting changes in dopamine-dependent behaviors relevant to neuropsychiatric risk, thereby advancing fundamental knowledge to inform mitigation strategies for early life stress effects.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $722.2k | 2/26/26 |