Project Grant R36DA064874
- Federal Project Grant Award Summary The University of Maryland, Baltimore received a $1.11 million Project Grant from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct joint decomposition analysis of multi-omic datasets related to substance use disorders (SUD) and human immunodeficiency virus (HIV) effects on brain circuitry and neuroinflammation. The project, which commenced September 1, 2025 and extends through May 31, 2030, will...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a $275,204 Project Grant to the University of Maryland, Baltimore on June 12, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279) funding mechanism. This research project, titled "The Impact of Perinatal Fentanyl on Dopamine Neuron Circuitry and Behavior," will be conducted through December 11, 2027, and addresses the urgent public health crisis of opioid use disorder among...
- Federal Project Grant Award Summary The University of Maryland, College Park received a $248,717 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) for the three-year period from August 1, 2025 through July 31, 2028. The award supports research investigating the neural mechanisms and circuits underlying orbitofrontal cortex (OFC) signaling in cognitive map formation. The research employs an odor-guided choice task...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of Maryland, Baltimore a Project Grant of $641,450 under the Drug Use and Addiction Research Programs (CFDA 93.279) effective July 15, 2025, with a completion date of March 31, 2030. This award funds research into the behavioral and neurobiological mechanisms of reciprocal social interactions in substance use disorders (SUDs). The primary deliverable is a comprehensive preclinical research study...
- Federal Grant Award Summary The University of Washington has received a $699,748 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), effective February 15, 2026 through November 30, 2030. This research project delivers comprehensive longitudinal neurodevelopmental assessment services examining the effects of prenatal cannabis exposure on infant brain development and growth trajectories during the critical first 18...
- Federal Grant Award Summary The University of Michigan received a $170,744 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) on June 17, 2025. This research initiative investigates the glucocorticoid receptor (GR) as a neuromolecular mechanism within the prelimbic cortex to nucleus accumbens core pathway that regulates inhibitory control deficits associated with substance use disorder (SUD). The project addresses...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded University of Maryland, Baltimore a $171,822 Project Grant effective July 15, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct the Effects of Prenatal and Postnatal Cannabis Use on Lactation and Maternal Bonding (LAMB) study. This five-year research initiative (concluding June 30, 2030) investigates the biological and behavioral effects of cannabis use during pregnancy and the...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded $4.63 million to The Research Foundation for the State University of New York (SUNY Downstate Health Sciences University) under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct longitudinal research examining the intersection of neighborhood conditions, neural circuits, and substance use disorder (SUD) behaviors across the early life course. The project, which commenced on September 30, 2025, and...
- Federal Project Grant Award Summary The Children's Hospital of Philadelphia Research Institute received a $534,000 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), effective September 1, 2025, through May 31, 2030. This research initiative investigates the lifespan effects of prenatal and perinatal opioid exposure on the brain's metabolic-epigenetic axis. The project employs innovative methodologies including...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded The Johns Hopkins University a Project Grant totaling $439,180 under the Drug Use and Addiction Research Programs (CFDA 93.279) for the period September 1, 2025 through August 31, 2027. This R21 high-risk/reward research grant supports an investigation titled "Deconvoluting Dopaminergic Neuronal-Glial Interactions in the Striatum." The project examines the intersection of HIV (human immunodeficiency...
The University of Maryland, College Park received a $107,090 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning February 15, 2026, with completion scheduled for February 14, 2028. This research project will investigate how trajectories of perinatal substance use (PSU) and perinatal depression (PD) interact to impact neonatal brain development, specifically focusing on infant hippocampal development. The study will employ longitudinal, person-centered data-driven analytical approaches to characterize the bidirectional interplay between PSU and PD across the perinatal period, moving beyond static clinical cutoffs to identify key risk windows and metrics that may inform clinical interventions with intergenerational benefits. The research will deliver three primary intellectual products: (1) empirical characterization of how PSU and PD reciprocally unfold over time during the perinatal period, determining whether within-subject or between-subject analytical models better capture bidirectional risk; (2) quantitative assessment of how PSU/PD comorbidity affects infant hippocampal volume and growth trajectories; and (3) comparative evaluation of developmental theoretical models (mismatch, cumulative stress, and mood entropy frameworks) to explain observed neurodevelopmental outcomes. This work directly supports NIDA's mission to develop new knowledge and approaches for understanding substance use prevention and treatment while addressing comorbid mental health conditions and their downstream effects on child development.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $107.1k | 2/6/26 |